Results 41 to 50 of about 19,024 (248)

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Etiology of Adult Female Acne–Systematic Review

Health Science Reports
Background Acne vulgaris is a common inflammatory disease of the skin. Acne occurring in > 25 years old is called “adult acne,” and it occurs more commonly in women than in men.
Anni Telkkälä, Suvi‐Päivikki Sinikumpu, Laura Huilaja   +2 more
doaj   +1 more source

A clinico-epidemiological study of adult acne: Is it different from adolescent acne?

Indian Journal of Dermatology, Venereology, and Leprology, 2012
Although acne is usually recognized as an adolescent skin disorder, the prevalence of adults with acne is increasing. There is surprisingly a paucity of data on the prevalence and clinical features of postadolescent acne in the adult Indian population.The clinical and epidemiological data of adult acne were evaluated with a view to establishing ...
Niti, Khunger, Chandan, Kumar
openaire   +2 more sources

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

How to treat acne in women with polycystic ovary syndrome (PCOS)? Review of the available literature

Journal of Education, Health and Sport, 2022
Acne vulgaris is one of the most common chronic skin diseases among people between 15 and 40 years of age.[i] It would seem that it is a typical disease of adolescence. However, it also very often affects adults.
Ewelina Zygmunt, Hubert Wróblewski, Aleksandra Zimna, Dariusz Chojęta, Anna Kozłowska   +4 more
doaj   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, Accepted Article.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week (W), double‐blind, placebo‐controlled, phase 3 POETYK PsA‐2 study
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

The Association Between Short-Term Air Pollution Exposure and Post-Adolescent Acne: The Evidence from a Time Series Analysis in Xi’an, China

Clinical, Cosmetic and Investigational Dermatology, 2021
Xiang Li,1,2,* Shu-Jie An,3,* Xiao-Ling Liu,1,* Ai-Ling Ji,4 Yi Cao,5 Ying Xiang,1 Xiang-Yu Ma,1 Qin Hu,1 Zhi-Quan Yuan,1 Ya-Fei Li,1 Yuan-Gang Lu,2 Tong-Jian Cai1 1Department of Epidemiology, College of Preventive Medicine, Army Medical ...
Li X, An SJ, Liu XL, Ji AL, Cao Y, Xiang Y, Ma XY, Hu Q, Yuan ZQ, Li YF, Lu YG, Cai TJ   +11 more
doaj  

Evaluation of Acne Quality of Life and Clinical Severity in Acne Female Adults [PDF]

Dermatology Research and Practice, 2010
Acne is a common disease especially among teenagers. It has a considerable psychological impact on affected individuals. The aim of this paper was to assess if the effect of acne on acne‐related quality of life is correlated to acne clinical severity.
openaire   +3 more sources

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Integrated targeted serum metabolomic profile and its association with gender, age, disease severity, and pattern identification in acne.

PLoS ONE, 2020
BACKGROUND:Westernized diet and nutritional metabolism are important in acne pathogenesis, especially in adult patients. However, clinical and basic data are lacking.
Min Hee Kim, In Jin Ha, Eunok Kim, Kyuseok Kim   +3 more
doaj   +1 more source