Results 121 to 130 of about 107,561 (313)

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Swiss Adult Congenital HEart disease Registry (SACHER) - rationale, design and first results [PDF]

, 2017
BACKGROUND: In 2013, a prospective registry for adults with congenital heart disease (CHD) was established in Switzerland, providing detailed data on disease characteristics and outcomes: Swiss Adult Congenital HEart disease Registry (SACHER). Its aim is
Francesca Bonassin, Harald Gabriel, Bouchardy, Judith, Gabriel, Harald, Schwerzmann, Markus, Tobler, Daniel, Dominik Stambach, Theresa Seeliger, Matthias Greutmann, Engel, Reto, Christoph auf der Maur, Schwitz, Fabienne, Oxenius, Angela, Rutz, Tobias, Oxenius, Angela; https://orcid.org/, Angela Oxenius, Tobias Rutz, Seeliger, Theresa, Greutmann, Matthias, Wustmann, Kerstin, Christine Attenhofer Jost, Judith Bouchardy, Stambach, Dominik, Auf der Maur, Christoph, Santos Lopes, Bruno, Markus Schwerzmann, Reto Engel, Bruno Santos Lopes, Kerstin Wustmann, Fabienne Schwitz, on behalf of SACHER, Attenhofer Jost, Christine, Kuen, Hans Peter, SACHER, Daniel Tobler, Hans-Peter Kuen, Bonassin, Francesca   +36 more
core   +1 more source

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects

, 2008
With the exception of studies on folic acid, little evidence is available concerning other nutrients in the pathogenesis of congenital heart defects (CHDs).
Rakhshandehroo, M., Ottenkamp, J., Steegers, Eric A. P., Smedts, Dineke, Steegers-Theunissen, Régine P. M., Verkleij-Hagoort, AC, Steegers, E.A.P., Steegers - Theunissen, Régine; id_orcid, Ottenkamp, J, Steegers, Eric, Steegers-Theunissen, R.P.M., Rakhshandehroo, M, de Vries, J.H.M., Ottenkamp, Jaap, Smedts, Huberdina P. M., Verkleij-Hagoort, Anna C., de Vries, Jeanne H. M., Rakhshandehroo, Maryam, Vries, J.H.M., de, de Vries, JHM, Verkleij-Hagoort, A.C., Smedts, H.P.M., Steegers - Theunissen, Régine   +22 more
core   +1 more source

Contact force sensing radiofrequency catheter ablation guided by electroanatomic mapping in pediatric patients with permanent junctional reciprocating tachycardia: A case series

Journal of Arrhythmia, 2023
Giovanni Domenico Ciriello, Diego Colonna, Emanuele Romeo, Maria Giovanna Russo, Berardo Sarubbi   +4 more
doaj   +1 more source

Factors associated with cardiovascular events after simultaneous liver–kidney transplant from the US Multicenter Simultaneous Liver–Kidney Transplant Consortium

Hepatology Communications, EarlyView., 2022
Abstract Cardiovascular disease is a leading complication after both liver and kidney transplantation. Factors associated with and rates of cardiovascular events (CVEs) after simultaneous liver–kidney transplant (SLKT) are unknown. This was a retrospective cohort study of adult SLKT recipients between 2002 and 2017 at six centers in six United Network ...
Jennifer Jo, Gonzalo Crespo, Dyanna Gregory, Jasmine Sinha, Jiaheng Xie, Min Zhang, John Magee, Pranab Barman, Yuval A. Patel, Aaron Schluger, Kara Walters, Scott Biggins, Natalia Filipek, Giuseppe Cullaro, Randi Wong, Jennifer C. Lai, Gabriel J. Perreault, Elizabeth C. Verna, Pratima Sharma, Lisa B. VanWagner   +19 more
wiley   +1 more source

Adults with congenital heart disease: the patients' perspective.

Over the last 50 years technical and other advances have resulted in more than 90% of children born with congenital heart disease (CHD) surviving and reaching adulthood.
Lyon, Joy E.
core  

Desaturation after Fontan procedure due to systemic venous collateral and improvement after closure with embolization

Clinical Case Reports
Key Clinical Message Systemic to pulmonary venous collaterals (SPVCs) are common findings in patients with Fontan and may be responsible for desaturation in this group of patients.
Alexandros Tsoutsinos, Felicia Kakava, Meletios Kanakis, George Samanidis, Stefanos Despotopoulos, George Vagenakis, Sotiria Apostolopoulou, John Papagiannis, Spyridon Rammos   +8 more
doaj   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source