Results 141 to 150 of about 8,578,623 (351)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
DENTAL HEALTH EDUCATION: For Dental Health Educators in School and Community Dental Health Programs with Special Consideration for the Education of Adults During Dental Treatment [PDF]
, 1961 David F. Striffler
openalex +1 more source
Critical adult education and community organizing: The case of diverse communities in Israel. [PDF]
J Community Psychol, 2022 Postan-Aizik D.
europepmc +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Adult Education in Transition: A Study of Institutional Insecurity.
, 1957 Ward S. Mason, Burton R. Clark
openalex +2 more sources
Social Economy, Trend or Reality. The event [PDF]
Annals of Philosophy, Social and Human Disciplines, 2012 Petru Vasile GAFIUC, +3 more
doaj
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
ChatGPT in healthcare education: a double-edged sword of trends, challenges, and opportunities
Discover EducationThe advancement of artificial intelligence (AI) tools has revolutionized teaching and learning, particularly in healthcare education, where they enhance pedagogy, foster immersive learning, and support healthcare provision.
Michael Agyemang Adarkwah +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source