Results 141 to 150 of about 2,726,109 (350)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Positive Adult Education, Learned Helplessness and the Pygmalion Effect. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Cobos-Sanchiz D   +3 more
europepmc   +1 more source

Does Comprehensive Education Work for the Long-term Unemployed? [PDF]

open access: yes
This paper evaluates the effects of comprehensive adult education on wage earnings of the long-term unemployed, an essentially unexplored issue. We use register data pertaining to a large sample of long-term unemployed persons in Sweden who either ...
Stenberg, Anders, Westerlund, Olle
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

General Education, Vocational Education, and Labor-Market Outcomes over the Life-Cycle [PDF]

open access: yes
Policy debates about the balance of vocational and general education programs focus on the school-to-work transition. But with rapid technological change, gains in youth employment from vocational education may be offset by less adaptability and thus ...
Eric A. Hanushek   +2 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Social Economy, Trend or Reality. The event [PDF]

open access: yesAnnals of Philosophy, Social and Human Disciplines, 2012
Petru Vasile GAFIUC,   +3 more
doaj  

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