Results 91 to 100 of about 986,800 (264)

Socioeconomic and citizenship inequalities in hospitalisation of the adult population in Italy.

open access: yesPLoS ONE, 2020
BackgroundHigher levels of hospital admissions among people with lower socioeconomic level, including immigrants, have been observed in developed countries.
Alessio Petrelli   +8 more
doaj   +1 more source

Preparing women for dead-end jobs? Vocational education and training (VET) for information and communication technology (ICT) jobs [PDF]

open access: yes, 2011
This paper discusses the role that vocational education and training (VET) in ICT subject areas plays in contributing to the gender and social class structuring of ICT occupations, focusing in particular on education and employment data from the UK.
Kirkup, Gill
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

The Many Faces of Lifelong Learning: Recent Education Policy Trends in Europe [PDF]

open access: yes, 2002
This article examines the rise of the discourse on lifelong learning across Europe and the variety of national policy trends which its rhetoric occludes. The ubiquitous presence of this meta-discourse in education and training policy-in-theory is seen as
Green, Andy
core   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Socio-demographic and behavioural risk factors of SARS- CoV-2 seropositivity in rural tribal population of Tripura: A population based cross-sectional study

open access: yesJournal of Family Medicine and Primary Care
Context: Population-based serosurveys are important tool to estimate proportion of population infected by SARS Cov-2 and it helps to understand various socio- demographic, behavioural factors associated it.
Subrata Baidya   +4 more
doaj   +1 more source

Determinants of oral self-care in the Brazilian adult population: a national cross-sectional study

open access: yesBrazilian Oral Research, 2017
: This study aims to investigate variables related to adherence to oral self-care in the Brazilian adult population. It is an exploratory study, using secondary data from a population-based survey on a representative sample of the adult population of the
Danielle Bordin   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A STUDY OF MINIMUM WAGE EMPLOYMENT IN IRELAND: THE ROLE OF WORKER, HOUSEHOLD AND JOB CHARACTERISTICS. ESRI SURVEY AND STATISTICAL REPORT SERIES, November 2017 [PDF]

open access: yes, 2017
This study uses Irish data from the Survey of Income and Living Conditions (SILC) to examine the factors underlying differences in the relative risk of being in receipt of the National Minimum Wage (NMW) among groups with relatively high rates of ...
McGuinness, Seamus   +2 more
core  

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