Results 151 to 160 of about 20,977 (214)

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

Developmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin, Estelle Balissat, Pauline Colombier, Lily Paillat, Maeva Dutilleul, Anne Camus   +5 more
wiley   +1 more source

Robot-navigated sacroiliac joint fusion as salvage surgery for pelvic fixation failure in adult spinal deformity surgery: patient series. [PDF]

J Neurosurg Case Lessons
Sharma A, Abd-El-Barr MM, Passias P, Shaffrey CI, Rocos B, Quist PF, Richardson W, Than KD.   +7 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Complications following thoracolumbar spinal surgery for adult spinal deformity in the setting of rheumatoid arthritis with minimum 2-year follow-up surveillance. [PDF]

J Craniovertebr Junction Spine
Shah NV, Beyer GA, Gedailovich S, Alam JS, Wolfert AJ, Krasnyanskiy B, Hollern DA, Desai R, Passias PG, Paulino CB, Lafage V, Challier V, Diebo BG.   +12 more
europepmc   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Do Publicly Available Risk Calculators Apply to Adult Spinal Deformity Surgery? [PDF]

J Clin Med
Pajak A, Samuel JT, Subramanian T, Merrill RK, Akosman I, Clohisy JC, Du J, Zhang B, Elysee J, Shahi P, Kim DN, Jordan Y, Knopp RL, Lovecchio FC, Kim HJ.   +14 more
europepmc   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

Epileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini, Evripidis Pityrigkas, Zoi Kallia, Georgia Pepe, Antonis Frontistis, Dimitrios Profer, Vasilios Kimiskidis   +6 more
wiley   +1 more source

Response to Letter to the Editor for "Nonoperative Management of the Adult Spinal Deformity Patient: A Biopsychosocial Intervention versus Care-as-usual - A Comparative Treatment-Based Cohort Study with One-Year Follow-Up". [PDF]

Global Spine J
Hoevenaars EHW, Beekhuizen M, Alanay A, Charles YP, Kleinstueck F, Obeid I, O'Dowd J, Pellisé F, Pizones J, Spruit M, de Kleuver M, van Hooff ML.   +11 more
europepmc   +1 more source

Shared molecular pathways in pediatric genetic epilepsies: Insights from a single‐center cohort of 80 patients

Epilepsia Open, EarlyView.
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher, Mathias Woidy, Franziska Plein, Tatjana Bierhals, Leonie von Elsner, Theresia Herget, Maja Hempel, Fanny Kortüm, Lev Grinstein, Julia V. Cramer, Jessika Johannsen, Jonas Denecke   +11 more
wiley   +1 more source