Results 141 to 150 of about 4,997 (303)

A rare cause of a common symptom, Anakinra is effective in the urticaria of Schnitzler Syndrome: a case report [PDF]

, 2008
Lisa A Devlin, Gary Wright, J David M Edgar, RJ Powell, B Haraoui, D Lipsker, HD de Koning, L Schnitzler, M Yamaguchi, VM Martinez-Taboada, HD de Koning, SW Schneider, PN Hawkins   +12 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Adult-onset Still’s disease masquerading as acute coronary syndrome: a case report and review of the literature

Journal of Medical Case Reports
Introduction Adult-onset Still’s disease is a rare systemic autoinflammatory disease. We present a case of a young man with a constellation of symptoms and myopericarditis as a complication of this disease.
Indigo Milne, Rhea Kanwar, Whitney Martin, Daniel Egert, Allison Leisgang, Shirley A. Albano-Aluquin, Maria P. Henao, Christine Kreider, Paddy Ssentongo   +8 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Prurigo Pigmentosa-like Skin Lesion in Adult-onset Still’s Disease: A Case Report and Literature Review

Siriraj Medical Journal, 2015
A report of a 26-year-old woman with adult-onset Still’s disease (AOSD) presenting with prolonged fever, arthralgia and reticulate papular eruptions on her abdomen and back without typical rash of AOSD.
Penvadee Pattanaprichakul
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

STILL'S DISEASE AND PREGNANCY: CURRENT STATE OF THE PROBLEM

Мать и дитя в Кузбассе
Systemic juvenile idiopathic arthritis and adult Still's disease are currently considered as a single autoinflammatory disease with inherited polygenic pattern – Still's disease (SD).
Виталий Борисович Цхай, Павел Анатольевич Шестерня   +1 more
doaj  

Adult Still's disease and squamous cell carcinoma in a 69-year-old woman. [PDF]

Pan Afr Med J, 2019
Marzouk S, Frikha O, Guermazi M, Snoussi M, Jallouli M, Bahloul Z.   +5 more
europepmc   +1 more source