Results 111 to 120 of about 1,914,795 (248)

PLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao   +10 more
wiley   +1 more source

Role of new vaccinators/pharmacists in life-course vaccination

open access: yesAnnals of Medicine
Background Vaccines against diseases such as herpes zoster, pneumococcus and influenza are broadly recommended for older adults, but uptake is frequently low.Vaccination Bottleneck Part of the reason may be that access to adult vaccination can be ...
T. Mark Doherty, Lois Privor-Dumm
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

“Smelltronics”—From Gas to Smell Sensing

open access: yesAdvanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono   +7 more
wiley   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

open access: yesAdvanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi   +5 more
wiley   +1 more source

Barriers to effective communication on adult vaccination: results of in-depth interviews with the population and healthcare professionals of the Arkhangelsk Oblast

open access: yesКардиоваскулярная терапия и профилактика
The effectiveness of communication with a doctor on vaccination often determines a patient's decision to vaccinate. However, the related difficulties and barriers remain insufficiently studied.Aim.
M. V. Lopatina   +8 more
doaj   +1 more source

Flax Composites With Improved Interfacial Strength Through Microbially Induced Mineral Precipitation

open access: yesAdvanced Materials, EarlyView.
A bio‐inspired biomineralization strategy introduces an additional hierarchy to flax fiber composites. By controlling microbe‐mediated mineral particle deposition through tuned salt concentrations, stress transfer within the natural fiber composite is enhanced.
Deniz Sayinbas   +5 more
wiley   +1 more source

The Association of Vaccination for Common Adult Infectious Diseases and Uptake of COVID-19 Vaccines among 5,006,851 Veterans, 20 December 2020–31 October 2021

open access: yesVaccines
Disparities in vaccination coverage for coronavirus disease 2019 (COVID-19) in the United States (U.S.) are consistent barriers limiting our ability to control the spread of disease, particularly those by age and race/ethnicity.
Brady W. Bennett   +2 more
doaj   +1 more source

Adult polio vaccination [PDF]

open access: yes
slides-02-23/Polio-02-Kidd-508 ...

core  

Ascertainment of childhood vaccination histories in northern Malawi.

open access: yes, 2008
OBJECTIVE: To assess factors related to recorded vaccine uptake, which may confound the evaluation of vaccine impact. METHODS: Analysis of documented vaccination histories of children under 5 years and demographic and socio-economic characteristics ...
Mwinuka, V   +36 more
core   +1 more source

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