Results 171 to 180 of about 9,751,042 (392)

SCURVY IN AN ADULT. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1907
Patient. —Male, American, aged 33, robust; height 5 feet 9 inches; weighed 173 pounds; complained of bleeding from the mouth and pain while chewing food. Condition had existed two weeks. History. —Negative family history; no hemophilia; no serious illness; denies lues. Examination.
openaire   +3 more sources

Virtually Every State Experienced Deteriorating Access to Care for Adults Over the Past Decade [PDF]

open access: yes, 2012
Presents state-by-state data on 2000-10 changes in the likelihood of non-elderly adults and a subgroup of uninsured adults having unmet medical needs due to cost, receiving a routine checkup, and having a dental ...
Dana Goin   +3 more
core  

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

open access: yesFEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu   +5 more
wiley   +1 more source

Symptoms and symptom clusters in patients with hepatocellular carcinoma and commonly used instruments: An integrated review

open access: yesInternational Journal of Nursing Sciences
Objective: This study aimed to synthesize the available knowledge of identifying hepatocellular carcinoma (HCC) symptoms and symptom clusters in patients with HCC and instruments used for these assessments to maximize symptom management.
Thitiporn Pathomjaruwat   +2 more
doaj  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

open access: yesMolecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park   +6 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Health Status of Hemodialysis Patients with End Stage Kidney Disease in Kirkuk City

open access: yesKufa Journal for Nursing Sciences
Background: Hemodialysis is a treatment for end-stage renal disease (ESRD) in which a machine filters waste and excess fluids from the blood for patients whose kidneys can no longer perform this function on their own. The health status of a hemodialysis
Mujda Najim Taha, Abid Salih Kumait
doaj   +1 more source

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