Once-Weekly Semaglutide in Adults with Overweight or Obesity.
New England Journal of Medicine, 2021 BACKGROUND Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed ...
J. Wilding +13 more
semanticscholar +1 more source
World guidelines for falls prevention and management for older adults: a global initiative
Age and Ageing, 2022 Background falls and fall-related injuries are common in older adults, have negative effects on functional independence and quality of life and are associated with increased morbidity, mortality and health related costs.
M. Montero‐Odasso +56 more
semanticscholar +1 more source
A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19
New England Journal of Medicine, 2020 Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection,
B. Cao +64 more
semanticscholar +1 more source
Tobacco Product Use Among Adults — United States, 2020
MMWR. Morbidity and mortality weekly report, 2022 Although cigarette smoking has declined over the past several decades, a diverse landscape of combustible and noncombustible tobacco products has emerged in the United States (1-4).
M. Cornelius +4 more
semanticscholar +1 more source
The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)
PharmacoEconomics (Auckland), 2021 The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg +6 more
semanticscholar +1 more source
World Journal of Surgical Oncology, 2017 Background Surgeons, in general, underestimate the replaced left hepatic artery (rLHA) that arises from the left gastric artery (LGA), compared with the replaced right hepatic artery (rRHA), especially in standard gastric cancer surgery.
Michihiro Yamamoto +7 more
doaj +1 more source
Biomedicines, 2023 Research conducted on individuals with depression reveals that major depressive disorders (MDDs) coincide with diminished levels of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) in the brain, as well as modifications in the subunit ...
Timur Liwinski +3 more
doaj +1 more source
Aquatic Hydrophilidae and Hydraenidae of Wisconsin (Coleoptera). I. Introduction, Key to Genera of Adults, and Distribution, Habitat, Life Cycle, and Identification of Species of \u3ci\u3eHelophorus\u3c/i\u3e Fabricius, \u3ci\u3eHydrochus\u3c/i\u3e Leach, and \u3ci\u3eBerosus\u3c/i\u3e Leach (Hydrophilidae), and Hydraenidae [PDF]
, 2017 The 3,920 Helophorus (Helophorinae) adults collected in Wisconsin included 16 species, two of which were new species. Helophorus orientalis and H. lacustris predominated.
Hilsenhoff, William L
core +2 more sources
Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia
New England Journal of Medicine, 2018 Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude +34 more
semanticscholar +1 more source
Targeting PI3K/AKT/mTOR Pathway in Breast Cancer: From Biology to Clinical Challenges
Biomedicines, 2023 Breast cancer (BC) is the most common women cancer and cause of cancer death. Despite decades of scientific progress in BC treatments, the clinical benefit of new drugs is modest in several cases. The phosphatidylinositol 3-kinase (PI3K)/protein kinase B
Krisida Cerma +10 more
doaj +1 more source