Results 11 to 20 of about 5,977,231 (321)

Palliative Care for Older Adults Hospitalized for Stroke From the Informal Caregivers' Perspectives

Journal of Cardiovascular Nursing, 2022
Background International guidelines have promoted palliative care (PC) for stroke survivors, but definition and implementation have been less than ideal. This practice gap is more prominent in China, where discussion of death remains taboo.
Jing Jing Su, R. Lin, J. Paguio, Angela Y. M. Leung, A. Molassiotis   +4 more
semanticscholar   +1 more source

Once-Weekly Semaglutide in Adults with Overweight or Obesity.

New England Journal of Medicine, 2021
BACKGROUND Obesity is a global health challenge with few pharmacologic options. Whether adults with obesity can achieve weight loss with once-weekly semaglutide at a dose of 2.4 mg as an adjunct to lifestyle intervention has not been confirmed ...
J. Wilding, R. Batterham, S. Calanna, M. Davies, L. V. Van Gaal, I. Lingvay, B. McGowan, J. Rosenstock, Marie T D Tran, T. Wadden, S. Wharton, K. Yokote, N. Zeuthen, R. Kushner   +13 more
semanticscholar   +1 more source

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

New England Journal of Medicine, 2020
Background No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection,
B. Cao, Ye-ming Wang, Danning Wen, Wen Liu, Jingli Wang, Guohui Fan, L. Ruan, Bin Song, Yanping Cai, M. Wei, Xing-wang Li, Jia’an Xia, Nanshan Chen, J. Xiang, Ting Yu, T. Bai, Xuelei Xie, Li Zhang, Caihong Li, Y. Yuan, Hua Chen, Huadong Li, Hanping Huang, Shengjin Tu, Fengyun Gong, Y. Liu, Yuan Wei, C. Dong, F. Zhou, Xiaoying Gu, Jiuyang Xu, Zhibo Liu, Yi Zhang, Hui Li, L. Shang, Ke Wang, Kunxia Li, Xia Zhou, Xuan Dong, Zhaohui Qu, S. Lu, Xujuan Hu, Shunan Ruan, S. Luo, Jing Wu, Lu Peng, Fang Cheng, L. Pan, Jun Zou, Chunming Jia, Juan Wang, Xia Liu, Shuzhen Wang, Xudong Wu, Qing Ge, Jingli He, Haiyan Zhan, Fang Qiu, Li Guo, Chaolin Huang, T. Jaki, F. Hayden, P. Horby, Dingyu Zhang, Chen Wang   +64 more
semanticscholar   +1 more source

Like My Aunt Dorothy: Effects of Conversational Styles on Perceptions, Acceptance and Metaphorical Descriptions of Voice Assistants during Later Adulthood [PDF]

, 2023
Little research has investigated the design of conversational styles of voice assistants (VA) for adults in their later adulthood with varying personalities. In this Wizard of Oz experiment, 34 middle-aged (50 to 64 years old) and 24 older adults (65 to 80 years old) participated in a user study at a simulated home, interacting with a VA using either ...
arxiv   +1 more source

World guidelines for falls prevention and management for older adults: a global initiative

Age and Ageing, 2022
Background falls and fall-related injuries are common in older adults, have negative effects on functional independence and quality of life and are associated with increased morbidity, mortality and health related costs.
M. Montero‐Odasso, N. van der Velde, F. Martin, M. Petrovic, M. Tan, J. Ryg, Sara G. Aguilar-Navarro, Neil B. Alexander, C. Becker, H. Blain, R. Bourke, I. Cameron, R. Camicioli, L. Clemson, J. Close, K. Delbaere, L. Duan, G. Duque, S. Dyer, E. Freiberger, D. Ganz, F. Gómez, J. Hausdorff, D. Hogan, S. Hunter, J. Jáuregui, N. Kamkar, R. Kenny, S. Lamb, N. Latham, L. Lipsitz, T. Liu-Ambrose, P. Logan, S. Lord, L. Mallet, D. Marsh, K. Milisen, Rogelio Moctezuma‐Gallegos, M. Morris, A. Nieuwboer, M. Perracini, F. Pieruccini‐Faria, Alison Pighills, C. Said, E. Sejdić, C. Sherrington, D. Skelton, Sabestina Dsouza, M. Speechley, S. Stark, C. Todd, B. Troen, T. V. D. van der Cammen, J. Verghese, Ellen Vlaeyen, Jennifer A Watt, T. Masud   +56 more
semanticscholar   +1 more source

Tobacco Product Use Among Adults — United States, 2020

MMWR. Morbidity and mortality weekly report, 2022
Although cigarette smoking has declined over the past several decades, a diverse landscape of combustible and noncombustible tobacco products has emerged in the United States (1-4).
M. Cornelius, Caitlin G. Loretan, Teresa W. Wang, Ahmed Jamal, D. Homa   +4 more
semanticscholar   +1 more source

Targeting PI3K/AKT/mTOR Pathway in Breast Cancer: From Biology to Clinical Challenges

Biomedicines, 2023
Breast cancer (BC) is the most common women cancer and cause of cancer death. Despite decades of scientific progress in BC treatments, the clinical benefit of new drugs is modest in several cases. The phosphatidylinositol 3-kinase (PI3K)/protein kinase B
Krisida Cerma, Federico Piacentini, Luca Moscetti, Monica Barbolini, Fabio Canino, Antonio Tornincasa, Federica Caggia, Sara Cerri, Alessia Molinaro, Massimo Dominici, Claudia Omarini   +10 more
doaj   +1 more source

Liver necrosis shortly after pancreaticoduodenectomy with resection of the replaced left hepatic artery

World Journal of Surgical Oncology, 2017
Background Surgeons, in general, underestimate the replaced left hepatic artery (rLHA) that arises from the left gastric artery (LGA), compared with the replaced right hepatic artery (rRHA), especially in standard gastric cancer surgery.
Michihiro Yamamoto, Masazumi Zaima, Hidekazu Yamamoto, Hideki Harada, Junichiro Kawamura, Masahiro Yamada, Tekefumi Yazawa, Junya Kawasoe   +7 more
doaj   +1 more source

T-DM1 efficacy in trastuzumab-pertuzumab pre-treated HER2 positive metastatic breast cancer patients: a meta-analysis

BMC Cancer, 2022
Background Current guidelines consider T-DM1 the standard 2nd line therapy for HER2 positive metastatic breast cancer (MBC) patients following trastuzumab (T) + pertuzumab (P) and taxane 1st line treatment.
Claudia Omarini, Federico Piacentini, Isabella Sperduti, Krisida Cerma, Monica Barbolini, Fabio Canino, Cecilia Nasso, Christel Isca, Federica Caggia, Massimo Dominici, Luca Moscetti   +10 more
doaj   +1 more source

A comparative evaluation of the efficacy and safety of Latanoprost-Optic and Xalatan used as monotherapy and combined with Dorzolamide-Optic for primary open-angle glaucoma under clinical practice conditions

Российский офтальмологический журнал, 2023
The number of ophthalmic antihypertensive drugs available in Russia is steadily increasing, which complicates the choice to be made by ophthalmologist practitioners.
D. P. Novikov, O. A. Frolov, A. S. Pokrovsky, V. V. Novikova   +3 more
doaj   +1 more source