Results 241 to 250 of about 10,055,911 (359)

Perspectives on creative well-being of older adults

, 2023
Dohee Lee, Inkeri Aula, Masood Masoodian
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Assessing the impact of the COVID-19 pandemic on recognition and testimony memory: differential effects in young and older adults. [PDF]

Front Psychol
Bonilla M, Flores Kanter PE, Vidal V, Jiménez ZA, Leon CS, Urreta Benitez FA, Brusco LI, Vázquez Chenlo A, Corfdir Y, García Bauza C, Forcato C.   +10 more
europepmc   +1 more source

‘You’re repulsive’: Limits to acceptable drunken comportment for young adults

, 2018
Sarah MacLean, Amy Pennay, Robin Room
openalex   +2 more sources

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis

The Lancet, 1992
D. Celermajer, K. Sørensen, V. Gooch, D. Spiegelhalter, O. Miller, I. Sullivan, J. Lloyd, J. Deanfield   +7 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The nutritional composition and impact on UK dietary intakes of meat and plant-based meat alternatives. [PDF]

NPJ Sci Food
Gouela M, Stergiadis S, Clegg ME.
europepmc   +1 more source

Polymorphic Expression of Cyp2C19 and Cyp2D6 in the Developing and Adult Human Brain Causing Variability in Cognition, Risk for Depression and Suicide: The Search for the Endogenous Substrates

, 2014
Magnus Ingelman‐Sundberg, Anna Persson, Marin M. Jukić   +2 more
openalex   +2 more sources

Immunotherapeutic approaches for the treatment of childhood, adolescent and young adult non‐Hodgkin lymphoma [PDF]

, 2016
Matthew J. Barth, Yaya Chu, Patrick J. Hanley, Mitchell S. Cairo   +3 more
openalex   +1 more source

Malignant gliomas in adults.

New England Journal of Medicine, 2008
P. Wen, S. Kesari
semanticscholar   +1 more source