Results 21 to 30 of about 5,977,231 (321)

Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia

open access: yesNew England Journal of Medicine, 2018
Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude   +34 more
semanticscholar   +1 more source

The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)

open access: yesPharmacoEconomics (Auckland), 2021
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg   +6 more
semanticscholar   +1 more source

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.

open access: yesBlood, 2017
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent
H. Döhner   +21 more
semanticscholar   +1 more source

New laparoscopic procedure for left-sided pancreatic cancer—artery-first approach laparoscopic RAMPS using 3D technique

open access: yesWorld Journal of Surgical Oncology, 2017
Background For left-sided pancreatic ductal adenocarcinoma (PDAC), radical antegrade modular pancreatosplenectomy (RAMPS) is a reasonable surgical approach for tumor-free margin resection and systemic lymph node clearance.
Michihiro Yamamoto   +7 more
doaj   +1 more source

Deep Adaptation of Adult-Child Facial Expressions by Fusing Landmark Features [PDF]

open access: yesIEEE Transactions on Affective Computing, 2023, 2022
Imaging of facial affects may be used to measure psychophysiological attributes of children through their adulthood for applications in education, healthcare, and entertainment, among others. Deep convolutional neural networks show promising results in classifying facial expressions of adults.
arxiv   +1 more source

Laboratory Predictors of Mortality in Patients with Heart Failure and Reduced Left Ventricular Ejection Fraction

open access: yesУкраїнський журнал серцево-судинної хірургії, 2023
Introduction. Heart failure (HF) is a growing epidemic with high morbidity and mortality rates. In general, mortality in patients with HF is 10.4% after 30 days from admission, 22% after 1 year, and 42.3% after 5 years, despite the introduction of new ...
Mariia V. Kucheriava   +1 more
doaj   +1 more source

Frailty in older adults: evidence for a phenotype.

open access: yesThe journals of gerontology. Series A, Biological sciences and medical sciences, 2001
BACKGROUND Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other characteristics, but it is ...
Linda P. Fried   +10 more
semanticscholar   +1 more source

Use of Continuous Glucose Monitoring in Patient with Coronary Artery Disease and Type 2 Diabetes Mellitus: Case Report

open access: yesУкраїнський журнал серцево-судинної хірургії, 2022
We present a clinical case of continuous monitoring in a patient with coronary artery disease and concomitant type 2 diabetes mellitus. A 75-year-old patient with a history of coronary artery bypass graft surgery more than 10 years ago was admitted to ...
Georgy B. Mankovsky   +5 more
doaj   +1 more source

Myocardial Revascularization in Patients with Coronary Artery Disease and Reduced Left Ventricular Ejection Fraction

open access: yesУкраїнський журнал серцево-судинної хірургії, 2022
The aim. To evaluate the short-term and long-term outcomes of myocardial revascularization – percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) – in patients with coronary artery disease (CAD) and heart failure (HF) with ...
Mariia V. Kucheriava   +1 more
doaj   +1 more source

AFFORCE: Actionable Framework for Designing Crowdsourcing Experiences for Older Adults [PDF]

open access: yes, 2022
In this article we propose a unique framework for designing attractive and engaging crowdsourcing systems for older adults, which is called AFFORCE (Actionable Framework For Crowdsourcing Experiences). We first categorize and map mitigating factors and barriers to crowdsourcing for older adults to finally discuss, present and combine system elements ...
arxiv   +1 more source

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