Results 21 to 30 of about 5,977,231 (321)
Tisagenlecleucel in Children and Young Adults with B‐Cell Lymphoblastic Leukemia
Background In a single‐center phase 1–2a study, the anti‐CD19 chimeric antigen receptor (CAR) T‐cell therapy tisagenlecleucel produced high rates of complete remission and was associated with serious but mainly reversible toxic effects in children and ...
S. Maude+34 more
semanticscholar +1 more source
The Economic Burden of Adults with Major Depressive Disorder in the United States (2010 and 2018)
The incremental economic burden of US adults with major depressive disorder (MDD) was estimated at $US210.5 billion in 2010 (year 2012 values). Following a similar methodology, this study updates the previous findings with more recent data to report the ...
P. Greenberg+6 more
semanticscholar +1 more source
The first edition of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults, published in 2010, has found broad acceptance by physicians and investigators caring for patients with AML. Recent
H. Döhner+21 more
semanticscholar +1 more source
Background For left-sided pancreatic ductal adenocarcinoma (PDAC), radical antegrade modular pancreatosplenectomy (RAMPS) is a reasonable surgical approach for tumor-free margin resection and systemic lymph node clearance.
Michihiro Yamamoto+7 more
doaj +1 more source
Deep Adaptation of Adult-Child Facial Expressions by Fusing Landmark Features [PDF]
Imaging of facial affects may be used to measure psychophysiological attributes of children through their adulthood for applications in education, healthcare, and entertainment, among others. Deep convolutional neural networks show promising results in classifying facial expressions of adults.
arxiv +1 more source
Introduction. Heart failure (HF) is a growing epidemic with high morbidity and mortality rates. In general, mortality in patients with HF is 10.4% after 30 days from admission, 22% after 1 year, and 42.3% after 5 years, despite the introduction of new ...
Mariia V. Kucheriava+1 more
doaj +1 more source
Frailty in older adults: evidence for a phenotype.
BACKGROUND Frailty is considered highly prevalent in old age and to confer high risk for falls, disability, hospitalization, and mortality. Frailty has been considered synonymous with disability, comorbidity, and other characteristics, but it is ...
Linda P. Fried+10 more
semanticscholar +1 more source
We present a clinical case of continuous monitoring in a patient with coronary artery disease and concomitant type 2 diabetes mellitus. A 75-year-old patient with a history of coronary artery bypass graft surgery more than 10 years ago was admitted to ...
Georgy B. Mankovsky+5 more
doaj +1 more source
The aim. To evaluate the short-term and long-term outcomes of myocardial revascularization – percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) – in patients with coronary artery disease (CAD) and heart failure (HF) with ...
Mariia V. Kucheriava+1 more
doaj +1 more source
AFFORCE: Actionable Framework for Designing Crowdsourcing Experiences for Older Adults [PDF]
In this article we propose a unique framework for designing attractive and engaging crowdsourcing systems for older adults, which is called AFFORCE (Actionable Framework For Crowdsourcing Experiences). We first categorize and map mitigating factors and barriers to crowdsourcing for older adults to finally discuss, present and combine system elements ...
arxiv +1 more source