Results 71 to 80 of about 5,977,231 (321)

Predicting the probability for falls in community-dwelling older adults using the Timed Up & Go Test.

Physical Therapy, 2000
BACKGROUND AND PURPOSE This study examined the sensitivity and specificity of the Timed Up & Go Test (TUG) under single-task versus dual-task conditions for identifying elderly individuals who are prone to falling. SUBJECTS Fifteen older adults with no
A. Shumway-cook, Sandy Brauer, M. Woollacott   +2 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Prognostic significance of delirium subtypes in critically ill medical and surgical patients: a secondary analysis of a prospective multicenter study

Journal of Intensive Care, 2022
Background The prognostic implication of delirium subtypes in critically ill medical and surgical patients is scarcely investigated. The objective was to determine how delirium subtypes are associated with hospital mortality and other clinical outcomes ...
Lisa Smit, Eveline J. A. Wiegers, Zoran Trogrlic, Wim J. R. Rietdijk, Diederik Gommers, Erwin Ista, Mathieu van der Jagt   +6 more
doaj   +1 more source

Inclusive Privacy Design for Older Adults Living in Ambient Assisted Living [PDF]

arXiv, 2022
Ambient assisted living (AAL) environments support independence and quality of life of older adults However, in an AAL environment, privacy-related issues (e.g., unawareness, information disclosure, and lack of support) directly impact older adults and bystanders (e.g., caregivers, service providers, etc.).
arxiv  

Physical activity and public health in older adults: recommendation from the American College of Sports Medicine and the American Heart Association.

Medicine & Science in Sports & Exercise, 2007
OBJECTIVE To issue a recommendation on the types and amounts of physical activity needed to improve and maintain health in older adults. PARTICIPANTS A panel of scientists with expertise in public health, behavioral science, epidemiology, exercise ...
M. Nelson, W. Rejeski, S. Blair, P. Duncan, J. Judge, A. King, C. Macera, C. Castaneda-Sceppa   +7 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Hypospadias: clinical approach, surgical technique and long-term outcome

BMC Pediatrics, 2021
Background Hypospadias is one of the most common congenital abnormalities in male newborn. There is no universal approach to hypospadias surgical repair, with more than 300 corrective procedures described in current literature.
Pier Luca Ceccarelli, Laura Lucaccioni, Francesca Poluzzi, Anastasia Bianchini, Diego Biondini, Lorenzo Iughetti, Barbara Predieri   +6 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Ectopic pregnancy treatment by combination therapy

Open Medicine, 2016
Detectability of early stages of ectopic pregnancies has increased due to improvements in ultrasonographic and biochemical techniques. Since the patients’ future procreative plans must be taken into consideration when commencing treatment, the goal of ...
Cymbaluk-Płoska Aneta, Chudecka-Głaz Anita, Kuźniak Sławomir, Menkiszak Janusz   +3 more
doaj   +1 more source

2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults

Circulation, 2013
Loria, Barbara E. Millen, Cathy A. Nonas, F. Xavier Pi-Sunyer, June Stevens, Victor J. Stevens, Karen A. Donato, Frank B. Hu, Van S. Hubbard, John M. Jakicic, Robert F. Kushner, Catherine M. Michael D. Jensen, Donna H. Ryan, Caroline M.
M. Jensen, D. Ryan, C. Apovian, J. Ard, Anthony G. Comuzzie, K. Donato, F. Hu, V. Hubbard, J. Jakicic, R. Kushner, C. Loria, B. Millen, C. Nonas, F. Pi‐Sunyer, J. Stevens, V. Stevens, T. Wadden, B. Wolfe, S. Yanovski, H. Jordan, Karima A. Kendall, L. Lux, R. Mentor-Marcel, Laura C. Morgan, M. Trisolini, J. Wnek, Jeffrey L. Anderson, J. Halperin, N. Albert, B. Bozkurt, R. Brindis, L. Curtis, D. DeMets, J. Hochman, R. Kovacs, E. Ohman, S. Pressler, F. Sellke, W. Shen, Sidney C. Smith, G. Tomaselli   +40 more
semanticscholar   +1 more source