Results 151 to 160 of about 1,673,984 (332)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Arte y Publicidad: Elementos para debate Art and Advertising: Issues for Debate
En este artículo se presentan algunos elementos para el debate en torno a la relación entre publicidad y arte. Algunos autores han señalado que la publicidad es el arte en la era de la muerte del arte, sin embargo, discutiremos esta afirmación tomando ...
Alejandra Walzer
doaj
Advancing into a future hospital pharmacy practice model: the value of the Basel Statements [PDF]
Josep M Segura
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
EARMA Statement in support of CoARA, the Coalition for Advancing Research Assessment
European Association of Research Managers and Administrators (EARMA)
openalex +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
WHO Statement on advancing the next series of studies to find the origins of SARS-CoV-2.
Prince Sultan Military Medical City
openalex +1 more source

