Results 181 to 190 of about 1,673,984 (332)

Consensus statement from the first RdRp Summit: advancing RNA virus discovery at scale across communities [PDF]

Justine Charon, Ingrida Olendraitė, Marco Forgia, Li Chuin Chong, Luke S. Hillary, Simon Roux, Anne Kupczok, Humberto Debat, Shoichi Sakaguchi, Rachid Tahzima, So Nakagawa, Artem Babaian, Aare Abroi, Nicolás Bejerman, Karima Ben Mansour, Katherine A. Brown, Anamarija Butković, Amelia Cervera, Florian Charriat, Guowei Chen, Yuto Chiba, Lander De Coninck, Tatiana A. Demina, Guillermo Domínguez‐Huerta, Jeremy Dubrulle, Serafín Gutiérrez, Erin Harvey, Fhilmar Raj Jayaraj Mallika, Dimitris Karapliafis, Shen Jean Lim, Sunitha Manjari Kasibhatla, Jonathon C. O. Mifsud, Yosuke Nishimura, Ayda Susana Ortiz-Báez, Milica Raco, Ricardo Rivero, Sabrina Sadiq, Shahram Saghaei, James Emmanuel San, Hisham Mohammed Shaikh, Ella T. Sieradzki, Matthew B. Sullivan, Yanni Sun, Michelle Wille, Yuri I. Wolf, Ņikita Zrelovs, Uri Neri   +46 more
openalex   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Parent Experience and Attitudes Towards Newborn Bloodspot Screening in Ireland. [PDF]

Int J Neonatal Screen
Bracken-Scally M, O'Loughlin A, Burns H.
europepmc   +1 more source

Correction to: “When I’m Thinking Straight, I Can Put Things in Place for When I’m Not.” | Exploring the Use of Advance Statements in First-Episode Psychosis Treatment: Young People, Clinician, and Carer Perspectives [PDF]

, 2020
Lee Valentine, Dawson Grace, Ingrid Pryor, Kate Buccilli, Marcus Sellars, Shona M. Francey, Magenta Simmons   +6 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Integrating Neurology, Palliative Care and Emergency Services in ALS: A Community-Integrated Neuropalliative Pathway in Modena, Italy. [PDF]

Brain Sci
Martucci G, Bonilauri SC, Canalini A, Baraldi M, Costantini L, Mora F, Vacondio P.   +6 more
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

What Do Older Adults with Frailty and Their Caregivers Want from Advance Care Planning Discussions? A Descriptive Qualitative Study. [PDF]

Healthcare (Basel)
Urquhart R, Kendell C, Vickery J, Hirsch E.   +3 more
europepmc   +1 more source

Recording Victim Video Statements as Evidence to Advance Legal Outcomes in Family Violence Cases (ReVEAL) 2.0: Case Characteristics and Initial Impact

, 2018
Bethany L. Backes, Anna Wasim, Jennifer LaMotte, Matt Kammer-Kerwick, Leila Wood, Micaela McDonald   +5 more
openalex   +1 more source