Results 221 to 230 of about 1,673,984 (332)

Consensus position statement on advancing the classification of patients and tests of cure in studies of antibiotic treatment of complicated urinary tract infections

Truls E. Bjerklund Johansen, Christina Bahrs, F. Bruyère, Tommaso Cai, Amelia Joseph, Béla Köves, David M Livermore, Alessandra Oliva, Àlex Soriano, Florian M. E. Wagenlehner, Per Henrik Zahl, Manuel Etienne, Deepak Batura, Charlotte Graugaard-Jensen, Keith S. Kaye, Jennifer Kranz, Massimiliano Lanzafame, José Medina-Polo, Francisco Javier Membrillo de Novales, Kurt G. Naber, J. Curtis Nickel, Laila Schneidewind, Zafer Tandoğdu   +22 more
openalex   +3 more sources

Evaluation of the novel multi-points surface thermometry cryoballoon in the treatment of paroxysmal atrial fibrillation. [PDF]

Front Cardiovasc Med
Bai L, Jia R, Sun X, Chan J, Wang X, Wang S, Liu M, Shen Y, Sun J, Cui K.   +9 more
europepmc   +1 more source

Dundee, Village of and International Union of Operating Engineers (IUOE), AFL-CIO, Local 832S (2007) [PDF]

, 2007

core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Response to letter regarding 'local large arterial perivascular adipose tissue metabolic and anatomical features are associated with hypertensive clinical outcomes: a PET/CT-Based study'. [PDF]

Ann Med
Long HY, Chen GD, Chen BQ.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Documentation of Advance Care Planning in Early Phase Cancer Clinical Trials: An Australian Single-Centre Experience. [PDF]

Cancers (Basel)
Huang N, Descallar J, Vo S, Lee SS, Wilkinson K, Roohullah A, Cooper A, Bray V, Chua W, Ní Chróinín D, Pal A.   +10 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Consensus statement on extracellular vesicles in liquid biopsy for advancing laboratory medicine [PDF]

Xingli Dong, Yusheng Lin, Kai Li, Gaofeng Liang, Xiaoyi Huang, Jingxuan Pan, Lu Wang, Dongmei Zhang, Tingjiao Liu, Tong Wang, Xiaomei Yan, Long Zhang, Xiaowu Li, Xiujuan Qu, Da Jia, Yong Li, Hao Zhang   +16 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source