Results 251 to 260 of about 1,673,984 (332)

Weekday-Weekend Shifts of Light/Dark Regimen Extend Sleep and Lifespan of <i>Drosophila melanogaster</i>. [PDF]

Nat Sci Sleep
Zakharenko LP, Petrovskii DV, Putilov AA.   +2 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Feasibility and acceptability of the Trans-theoretical Model-based advance care planning for community-dwelling older adults with chronic diseases in China: a randomized controlled trial. [PDF]

Front Public Health
Feng S, Chen J, Zhao M, Zhuo Y, Zhao X, Wang X, Qiao B.   +6 more
europepmc   +1 more source

Orange and Ulster Counties BOCES District and Orange and Ulster Counties BOCES Assistant Teachers Association (2000) [PDF]

, 2000

core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Project DECIDE II: evaluating the efficacy of supported advance care decision making within routine care in dementia: a randomized controlled trial. [PDF]

BMC Med Ethics
Athanasiadi E, Thyrian JR, Florack J, Theile-Schürholz A, Karneboge J, Müller T, Kleinke K, Kremer S, Boes C, Böhm H, Herder-Peyrounette A, Kremer M, Sander C, Müller-Späth R, Ullrich H, Boekholt M, Hassenzahl M, Albers R, Forstmeier S, Schaper P, Haberstroh J.   +20 more
europepmc   +1 more source

1779TH COUNCIL MEETING - AGRICULTURE - BRUSSELS, 18 AND 19 JULY 1994- PRESIDENT: MR JOCHEN BORCHERT, MINISTER FOR FOOD, AGRICULTUREAND FORESTRY OF THE FEDERAL REPUBLIC OF GERMANY. PRES/94/147, 19/07/1994 [PDF]

, 1994

core  

Invited Editorial: Uniting the vision and aging sectors to advance healthy aging and eye health—The Manila Statement

Vânia de la Fuente-Núñez, Brandon A M Ah Tong, Amanda Davis, Lisa Keay, Drew Keys, Casey McCowan   +5 more
openalex   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Reflections on the role of AI in Alzheimer's disease research: Addressing inclusivity, causality, and ethical considerations. [PDF]

J Prev Alzheimers Dis
Chen M, Han Y.
europepmc   +1 more source