Results 21 to 30 of about 5,496,645 (302)

Observed and Predicted Risk of Breast Cancer Death in Randomized Trials on Breast Cancer Screening. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:The role of breast screening in breast cancer mortality declines is debated. Screening impacts cancer mortality through decreasing the number of advanced cancers with poor diagnosis, while cancer treatment works through decreasing the case ...
Philippe Autier   +4 more
doaj   +1 more source

Preventative therapies for healthy women at high risk of breast cancer [PDF]

open access: yes, 2014
Ivana Sestak Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, UKAbstract: Tamoxifen has been shown to reduce the risk of developing estrogen receptor (ER)-positive ...
Sestak I, Sestak, I
core   +1 more source

ABC4 Consensus: First Latin American Meeting—Assessment, Comments, and Application of Its Recommendations

open access: yesJCO Global Oncology, 2020
Breast cancer accounts for a high burden among all the neoplasms in Latin America, with more-advanced stages at presentation, which could result in high mortality rates.
Henry L. Gomez   +5 more
doaj   +1 more source

Management of advanced breast cancer

open access: yesAnnals of Oncology, 2007
Metastatic breast cancer (MBC) is usually considered an incurable situation, for which treatments chosen to control the disease, should take into account the maintenance of a good quality of life. The end points of treatment of patients with MBC are influenced by consideration about efficacy and toxicity of the different therapeutic options.
L, Orlando   +7 more
openaire   +2 more sources

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium.

open access: yes, 2007
Association studies in large series of breast cancer patients can be used to identify single-nucleotide polymorphisms (SNP) contributing to breast cancer susceptibility.
Pharoah, Paul DP   +22 more
core   +1 more source

Knowledge in Motion: A decade reviewed, a future defined – The ABC Global Alliance 2015–2025 Decade Report and 2025–2035 Global Charter

open access: yesBreast
Breast cancer remains one of the most significant global health challenges, with approximately 2.3 million new cases diagnosed and 666,000 deaths every year. Advanced breast cancer (ABC) – encompassing locally advanced and metastatic disease – represents
Fatima Cardoso   +4 more
doaj   +1 more source

Prognostic and predictive value of TP53 mutations in node-positive breast cancer patients treated with anthracycline- or anthracycline/taxane-based adjuvant therapy : results from the BIG 02-98 phase III trial [PDF]

open access: yes, 2012
Introduction: Pre-clinical data suggest p53-dependent anthracycline-induced apoptosis and p53-independent taxane activity. However, dedicated clinical research has not defined a predictive role for TP53 gene mutations. The aim of the current study was to
Viale, Giuseppe   +16 more
core   +2 more sources

Resisting ethnic inequities in advanced breast cancer: A call to action

open access: yes, 2022
Māori women with advanced breast cancer are less than half as likely as their Pākehā counterparts to reach the five-year survival mark. We argue that this inequity is unacceptable.
Kereama-Royal, Irene   +5 more
core   +1 more source

Microbiome and Breast Cancer: New Role for an Ancient Population

open access: yesFrontiers in Oncology, 2020
There are many risk factors associated with breast cancer (BC) such as the familial history of BC, using hormone replacement therapy, obesity, personal habits, and other clinical factors; however, not all BC cases are attributed to these risk factors ...
Zahra Eslami-S   +6 more
doaj   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani   +7 more
wiley   +1 more source

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