Results 131 to 140 of about 1,089,379 (264)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Advance care planning impact on caregivers and end-of-life care in advanced cancer. [PDF]

J Natl Cancer Inst
Crowley F, Belin S, Wang T, Applebaum A, Ferrell B, Flowers R, Sudore R, White D, Crowley-Makota M, Hammes B, Arnold R, Schenker Y.   +11 more
europepmc   +1 more source

Corrigendum: Overall Survival Prediction of Advanced Cancer Patients by Selection of the Most Significant Baseline Serum Biomarker Combination

Pathology and Oncology Research, 2022
Daniel Deme, Sandor Kovacs, Andras Telekes   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Bridging preclinical and clinical fluorescence-guided surgery with advanced cancer vision goggles. [PDF]

Npj Imaging
Zhang H, Xu X, Ta C, Zurutuza I, Gautam KS, Hongsermeier C, Blasi N, Voorugonda S, Mukherjee-Roy N, Gao J, Sumer B, Akers WJ, Achilefu S.   +12 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Oncolytic myxoma virus and engineering strategies for advanced cancer immunotherapy. [PDF]

iScience
Trujillo Yeriomenko AD, Isaeva AS, Idota EE, Zhivoderov SP, Yurkov SG, Malogolovkin AS.   +5 more
europepmc   +1 more source

Research progress on death anxiety in advanced cancer patients

Huli yanjiu, 2023
LIU Hui, LIU Zhili, WU Xiaoying, LI Xiaomin, YING Wenjuan   +4 more
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Digital Intervention for Electronic Patient-Reported Outcomes in Advanced Cancer: Mixed Methods Study. [PDF]

JMIR Cancer
Sauer C, Sauer S, Doll ES, Zschäbitz S, Raue JS, Turni M, Bugaj TJ, Hiller K, Maatouk I.   +8 more
europepmc   +1 more source