Results 231 to 240 of about 2,075,210 (312)

Patient-reported discordance between care goals and treatment intent in advanced cancer. [PDF]

Cancer
Shah MP, Wenger NS, Glaspy J, Hays RD, Sudore RL, Rahimi M, Gibbs L, Anand S, Tseng CH, Walling AM.   +9 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

MyPainPal, a Novel mHealth App to Improve Pain in Patients With Advanced Cancer: Single-Arm Pilot Study.

JMIR Cancer
Azizoddin DR, Hassett M, Anderson KS, Kessler D, Wright A, Gorra M, Kematick B, Chua I, Brandoff D, Lally K, Nabati L, MacIsaac S, Tulsky JA, Enzinger A.   +13 more
europepmc   +1 more source

Physical fitness and body composition assessments in advanced cancer patients undergoing exenterative surgery - A pilot cohort study. [PDF]

Colorectal Dis
Looby M, Matthews L, West CT, Khan K, Ansell G, Donovan K, Wood L, Tapley P, Lewis R, Stoddard K, Grocott MPW, Jack S, Yano H, Levett D, Mirnezami A, West MA.   +15 more
europepmc   +1 more source

Advanced renal cell cancer

Kidney International, 1981
openaire   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

SERS-guided photodynamic therapy: pioneering strategies in advanced cancer diagnosis and treatment. [PDF]

Discov Nano
Jaikumar T, George S, Saju H, Raj R, Nisarga R, Sontakke S, Sangshetti J, Prakash J, Arote RB.   +8 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Immune checkpoint inhibitor therapy in advanced cancer: clinical association of irAEs type, inflammatory markers and efficacy. [PDF]

Front Immunol
Qian M, Ma P, Zhao Y, Jiang H, Gao L, Lin G, Duan D, Guo J.   +7 more
europepmc   +1 more source