Results 91 to 100 of about 4,338,794 (311)
Longitudinal Forces in Concrete Structures
Budownictwo i ArchitekturaTension forces are practically present in each concrete element. The phenomenon is due to the loss of hydration heat, concrete shrinkage and temperature drop which produces shortening of the components.
Piotr Noakowski
doaj
Experimental evaluation of combustor concepts for burning broad property fuels [PDF]
A baseline CF6-50 combustor and three advanced combustor designs were evaluated to determine the effects of combustor design on operational characteristics using broad property fuels.
Dodds, W. J. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Mining extreme properties from a large metamaterial database
Nature CommunicationsTruss metamaterials exhibit a wide range of properties due to their unique node-strut architectures, which are artificially engineered through a delicate design process.
Jiaxin Chen +6 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Journal of Engineered Fibers and FabricsUsing ABAQUS software as a tool and 225/60R18 tire as the research object, a finite element model of the tire was established and longitudinal slip simulation was conducted based on the completion of longitudinal slip and rubber material tests.
Jun-Ling Meng +5 more
doaj +1 more source
Research progress on continuum topology optimization for lightweight structure design
Xibei Gongye Daxue XuebaoIn order to sort and study the continuum topology optimization methods in the lightweight design of mechanical structures, the main research results achieved in this field at home and abroad in recent years are analyzed and reviewed.
ZHANG Lei +6 more
doaj +1 more source
Magnetic suspension and balance system advanced study, 1989 design [PDF]
The objectives are to experimentally confirm several advanced design concepts on the Magnetic Suspension and Balance Systems (MSBS). The advanced design concepts were identified as potential improvements by Madison Magnetics, Inc.
Abdelsalam, Moustafa K. +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source