Results 81 to 90 of about 20,657 (256)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A Multimodal Recurrent Model for Driver Distraction Detection
Applied SciencesDistracted driving is a significant threat to road safety, causing numerous accidents every year. Driver distraction detection systems offer a promising solution by alerting the driver to refocus on the primary driving task.
Marcel Ciesla, Gerald Ostermayer
doaj +1 more source
An Evolutionary Approach to Driving Tendency Recognition for Advanced Driver Assistance Systems
MATEC Web of Conferences, 2016 Driving tendency recognition is important for constructing Advanced Driver Assistance Systems (ADAS). However, it had not been a lot of research using vehicle sensing data, due to the high difficulty to define it. In this paper, we attempt to improve the
Lee Jong-Hyun, Ahn Chang Wook
doaj +1 more source
IEEE Access, 2019 Advanced Driver Assistance Systems (ADAS), created for enhancing the driving experience and actively preventing road crashes, have been progressively incorporated in vehicle designing essentially during the last decade.
Ignacio Lijarcio +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Single-Vehicle Trajectory Prediction: A Review and Experimental Embedded Assessment
IEEE Open Journal of Vehicular TechnologyDue to technological advances in the automotive field, advanced driver assistance systems have attracted increasing interest from various research and development entities.
Oumaima Skalli +3 more
doaj +1 more source
Factors Influencing Trust in Advanced Driver Assistance Systems for Current Users. [PDF]
Proc Hum Factors Ergon Soc Annu Meet, 2023 DeGuzman CA, Donmez B.
europepmc +1 more source