Results 51 to 60 of about 20,653 (256)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Machine Learning with ApplicationsThe recent advancements in Advanced Driver Assistance Systems (ADAS) have significantly contributed to road safety and driving comfort. An integral aspect of these systems is the detection of driver anomalies such as drowsiness, distraction, and ...
Tumlumbe Juliana Chengula +5 more
doaj +1 more source
Safety Assessment of Driver Assistance Systems
European Journal of Transport and Infrastructure Research, 2001 This paper reviews issues in and procedures for the safety evaluation of in-vehicle Advanced Driver Assistance Systems. Contrasts are drawn between the two main areas of driver assistance systems — on the one hand information systems which interact with ...
O.M.J Carsten, L. Nilsson
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Enhancement of Yaw Moment Control for Drivers with Excessive Steering in Emergency Lane Changes
Applied SciencesWhen a ground vehicle runs at high speeds, even a slight excess in the wheel steering angle can immediately cause the vehicle to slide sideways and lose control.
Shou-Tao Peng +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Instances of Failures, Maintenance, and Repair in Smart Driving
Tecnoscienza, 2016 The paper focuses on technology designers’ representations and discourses about advanced driving assistance systems (ADAS). This issue has been empirically explored by means of seven in-depth interviews with academic experts in intelligent transportation
Oana Stefana Mitrea
doaj +1 more source