Results 161 to 170 of about 1,724 (248)

For Goodness' Sake: The Coloniality of Research Ethics in Biological Anthropology

open access: yesAmerican Journal of Biological Anthropology, Volume 190, Issue 4, August 2026.
ABSTRACT Modern science has emerged in relation with European colonization whereby virtuous logics have often animated dis/possessions and governing authorities over Indigenous Peoples and their territories. Indigenous Peoples have long resisted extractive and exploitative scientific practices.
Rick W. A. Smith, Jessica Kolopenuk
wiley   +1 more source

Early identification of vascular cognitive impairment from a multimodal perspective: a combined diagnosis from targeted cognitive assessments, imaging biomarkers, and molecular fluid biomarkers to ecological behavioral characteristics

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Vascular cognitive impairment (VCI), the second leading cause of dementia, is characterized by heterogeneous pathophysiology and a potentially reversible early phase, underscoring the need for timely identification. This review synthesizes advances across four complementary domains – targeted cognitive assessments, imaging biomarkers ...
Wenqi Song   +8 more
wiley   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2885-2898, August 2026.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

Assessing the Feasibility of a Self‐Management Intervention for Individuals With Advanced Prostate Cancer and Comorbid Type II Diabetes Mellitus

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Background Many older adults with cancer have at least one comorbidity. Type II diabetes mellitus (T2DM) is a common comorbidity among patients with prostate cancer (PC) and represents an important consideration in this population. Comorbid T2DM can negatively impact cancer‐specific outcomes for patients, suggesting the need for better ...
Amy L. Shaver   +15 more
wiley   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

open access: yesEuropean Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato   +2 more
wiley   +1 more source

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