Results 91 to 100 of about 2,368,347 (279)

OPA1 increases the risk of normal but not high tension glaucoma

, 2010
Background Primary open angle glaucoma is a progressive optic neuropathy characterised by the selective loss of retinal ganglion cells, pathological optic disc cupping and visual field defects.
Griffiths, P. G., Birch, M. K., Andrews, R. M., Chinnery, P. F., Hudson, G., Yu-Wai-Man, P., Stewart, J .D.   +6 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

An Alternate Technique for Goniotomy

Journal of Ophthalmic & Vision Research, 2022
Kouros Nouri-Mahdavi
doaj   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Comparing the Surgical Outcomes of Combined Kahook Dual Blade (KDB) Phacoemulsification Versus Non-Penetrating Deep Sclerectomy (NPDS) Phacoemulsification for Advanced Glaucoma with Co-Existing Cataract

TNOA Journal of Ophthalmic Science and Research
Purpose: To compare the 2-year efficacy and safety of Kahook dual blade (KDB) phacoemulsification and non-penetrating deep sclerectomy (NPDS) combined with phacoemulsification for advanced open angle glaucoma (OAG) and co-existing cataract.
Sharmila Rajendrababu, Kavitha Mamchimsetti, Noorul Hidaya, K. Balagiri Sundar, Vijayalakshmi A. Senthilkumar   +4 more
doaj   +1 more source

Current surgical methods for advanced glaucoma [PDF]

Orvosi Hetilap, 2013
The author summarizes the most effective types of glaucoma surgery in advanced glaucoma. In high pressure advanced glaucoma a low target intraocular pressure is to be set. The most effective method of reaching this target pressure level is mitomycin C trabeculectomy combined with effective pre- and postoperative antiinflammatory treatment. However, in
openaire   +2 more sources

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

Multivariate normative comparison, a novel method for improved use of retinal nerve fiber layer thickness to detect early glaucoma

, 2022
Purpose: Detection of early glaucoma remains limited with the conventional analysis of the retinal nerve fiber layer (RNFL). This study assessed whether compensating the RNFL thickness for multiple demographic and anatomic factors improves the detection ...
Wong, Damon, Tham, Yih Chung, Soh, Zhi Da, Cheng, Ching-Yu, Aung, Tin, Nongpiur, Monisha E., Li, Chi, Thakur, Sahil, Fischer, Georg, Husain, Rahat, Schwarzhans, Florian, Chua, Jacqueline, Majithia, Shivani, Sng, Chelvin C. A., Schmetterer, Leopold, Crowston, Jonathan G., Perera, Shamira A., Vass, Clemens, Jonathan G. Crowston, Shivani Majithia, Chi Li, Clemens Vass, Sahil Thakur, Georg Fischer, Ching-Yu Cheng, Shamira A. Perera, Chelvin C.A. Sng, Jacqueline Chua, Damon Wong, Monisha E. Nongpiur, Florian Schwarzhans, Rahat Husain, Leopold Schmetterer, Yih Chung Tham, Tin Aung, Zhi Da Soh   +35 more
core   +1 more source

starU‐Net: An enhanced U‐Net architecture with star operation and multi‐view fusion for improved vessel segmentation

VIEW, EarlyView.
Low‐contrast capillaries are often missed or fragmented by segmentation models, so we developed a shallow four‐level starU‐Net that combines star operation‐based feature extraction with dynamic snake convolution‐based multi‐view fusion for improved thin vessel continuity.
Mengwei Bai, Li Tong, Jing Lin, Peng Huang   +3 more
wiley   +1 more source

Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis

VIEW, EarlyView.
In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian, Keke Zhang, Wenwen He, Yan Ke, Yi Lu, Xiangjia Zhu   +5 more
wiley   +1 more source