Results 41 to 50 of about 65,427 (291)

Genetic association at the 9p21 glaucoma locus contributes to sex bias in normal-tension glaucoma [PDF]

, 2016
Purpose: Many genome-wide association studies have identified common single nucleotide polymorphisms (SNPs) at the 9p21 glaucoma locus (CDKN2B/CDKN2B-AS1) to be significantly associated with primary open-angle glaucoma (POAG), with association being ...
Burdon, K., Casson, R., Craig, J., Fitzgerald, J., Fogarty, R., Graham, S., Healey, P., Hewitt, A., Landers, J., Macgregor, S., Mackey, D., Mills, R., Mitchell, P., Ng, S., Ridge, B., Souzeau, E., Wang, J., Zhou, T.   +17 more
core   +1 more source

Prognostic importance of endothelin-1 and endothelin receptor: a plasma levels in the early perimetric stage of primary open-angle glaucoma

Biotechnology & Biotechnological Equipment, 2018
An increasing amount of data suggests a role of the eye vascular system and oxidative stress in glaucoma pathogenesis. Reports have suggested endothelin-1 (ET-1) and its receptor (ETR-A) as possible glaucoma biomarkers. This study explored the diagnostic
Bilyana Mihaylova, Anton Vassilev, Galina Dimitrova, Charita Rankova-Yotova, Iva Petkova, Stanislava Ivanova, Alexander Oscar   +6 more
doaj   +1 more source

Reproducibility of retinal nerve fiber layer measurements across the glaucoma spectrum using optical coherence tomography

Indian Journal of Ophthalmology, 2015
Purpose: The purpose was to determine intra-session and inter-session reproducibility of retinal nerve fiber layer (RNFL) thickness measurements with the spectral-domain Cirrus optical coherence tomography (OCT) ® (SD-OCT) in normal and glaucomatous eyes,
Jayesh Vazirani, Sushmita Kaushik, Surinder Singh Pandav, Pramod Gupta   +3 more
doaj   +1 more source

To compare and correlate visual field changes detected by perimetry with retinal nerve fiber layer and ganglion cell layer thickness observed using spectral domain optical coherence tomography in primary open angle glaucoma

TNOA Journal of Ophthalmic Science and Research, 2021
Aim: To evaluate the damage pattern of retinal ganglion cells at different stages of glaucoma in patients with primary open-angle glaucoma (POAG) by observing peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell layer-inner plexiform ...
Priya Gupta, Anita Minj, Suprava Das, Pradeep Kumar Panigrahi   +3 more
doaj   +1 more source

Precise Control of Drug Release in Machine Learning‐Designed Antibody‐Eluting Implants for Postoperative Scarring Inhibition in Glaucoma

Advanced Healthcare Materials, EarlyView.
We developed a micro‐sized, biocompatible implant for postoperative sustained delivery of anti‐fibrotic antibodies in glaucoma surgery. Machine learning‐guided optimization of polymer composition, implant geometry, and porosity enabled precise control of drug release.
Mengqi Qin, Wenbing Jiang, Kai Xin Thong, Zeynep Ulker, Brihitejas Patel, Cynthia Yu‐Wai‐Man   +5 more
wiley   +1 more source

Linking neural and clinical measures of glaucoma with diffusion magnetic resonance imaging (dMRI).

PLoS ONE, 2019
PurposeTo link optic nerve (ON) structural properties to clinical markers of glaucoma using advanced, semi-automated diffusion magnetic resonance imaging (dMRI) tractography in human glaucoma patients.MethodsWe characterized optic neuropathy in patients ...
Nathaniel Miller, Yao Liu, Roman Krivochenitser, Bas Rokers   +3 more
doaj   +1 more source

Association of severity of primary open-angle glaucoma with serum vitamin D levels in patients of African descent. [PDF]

, 2019
PurposeTo study the relationship between primary open-angle glaucoma (POAG) in a cohort of patients of African descent (AD) and serum vitamin D levels.MethodsA subset of the AD and glaucoma evaluation study III (ADAGES III) cohort, consisting of 357 ...
ADAGES III Genomics Study Group, Arzumanyan, Zorayr, Ayyagari, Radha, Chen, Yii-der I, Dirkes, Keri, Dubiner, Harvey, Feldman, Robert, Girkin, Christopher A, Guo, Xiuqing, Hai, Yang, Hammel, Naama, Holman, Matt, Liebmann, Jeffrey M, Rotter, Jerome I, Slight, Rigby, Taylor, Kent D, Weinreb, Robert N, Zangwill, Linda M   +17 more
core  

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor

Advanced Science, EarlyView.
Nanosecond laser irradiation of the clinically approved dye indocyanine green (ICG) enables light‐guided nanoparticle transport within the vitreous humor. The combined use of ICG and pulsed laser illumination induces localized convection and thermophoresis, directing particles toward illuminated regions.
Léa Guerassimoff, Yera Ussembayev, Louise De Clerck, Deep Punj, Martijn van den Broek, Filip Beunis, Katrien Remaut, Kevin Braeckmans, Stefaan C. De Smedt, Félix Sauvage   +9 more
wiley   +1 more source

Plasma endothelin-1 and endothelin-A receptor concentrations in patients with primary open-angle glaucoma

Biotechnology & Biotechnological Equipment, 2017
Endothelin-1 (ET-1) is a potent vasoconstrictor and is considered to have a key role in the regulation of ocular perfusion and glaucoma pathogenesis. High ET-1 and ETA-receptor levels are reported in patients with primary open-angle glaucoma (POAG).
Bilyana Mihaylova, Iva Petkova, Charita Rankova-Yotova, Galina Dimitrova, Ivan Tanev, Stanislava Ivanova, Adelina Tsakova, Dobrin Svinarov   +7 more
doaj   +1 more source