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Therapeutic advances in heart failure

Cardiovascular Drugs and Therapy, 1988
Annual mortality from congestive heart failure ranges from 15% to 60%, depending on the severity of the left ventricular damage and underlying disease. Most controlled trials have been too small to detect any beneficial effect on survival from the newer vasodilator and inotropic drugs.
T, Meinertz, H, Drexler, H, Just
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Recent advances in heart failure

Current Opinion in Cardiology, 2018
Acute heart failure continues to be a challenge as there is limited benefit of numerous agents that have been tested. Cardiac resynchronization therapy remains standard of care, yet timing and need for implantable cardiac defibrillator has been brought into question with the recent randomized trials.
Mahwash, Kassi   +2 more
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Management of advanced heart failure

Clinical Cornerstone, 2000
Congestive heart failure (CHF) due to progressive systolic dysfunction has become a modern-day epidemic. Despite the increased incidence and prevalence, significant progress has been made in the past 10 to 15 years in the treatment of CHF at all stages. The current outlook for patients with newly diagnosed, mild heart failure is encouraging.
Adrian B, Van Bakel, Geoffrey, Chidsey
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Advances in Heart Failure Surgery

Future Cardiology, 2005
Heart failure is a major public health problem in the USA and in most Western countries. Nearly 5 million patients in the USA have heart failure with approximately 500,000 patients being diagnosed for the first time each year. Medical therapy is the first-line treatment, and surgery is considered when medical therapy fails or a clear mechanical cause ...
Nicholas C, Dang   +2 more
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Advanced Heart Failure

Heart Failure Clinics, 2016
Heart failure remains one of the most important public health problems in the developed world, with increasing prevalence, high costs, and poor outcomes. Although survival after the diagnosis of heart failure has improved, approximately 50% of patients still die within 5 years after initial diagnosis.
Sunit-Preet Chaudhry, Garrick C. Stewart
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Treatment of Advanced Heart Failure

Cardiology in Review, 2000
The incidence of chronic heart failure has increased, with a corresponding increase in morbidity and mortality, and has made a substantial financial impact on our society. Improved therapy for heart failure has resulted in a significant prolongation of survival, a decreased number of hospitalizations, and an enhanced quality of life for many patients ...
M, Jessup, S, Brozena
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Advances in heart failure management

Medicina Clínica (English Edition)
Heart failure is a pathological condition characterized by substantial prevalence and mortality, particularly in the Western world. Over recent decades, both pharmacological and non-pharmacological interventions have emerged, significantly enhancing patient survival and overall quality of life.
José Luis, Zamorano   +1 more
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Management of advanced heart failure: a review

Expert Review of Cardiovascular Therapy, 2018
Heart failure (HF) has become a global pandemic. Despite recent developments in both medical and device treatments, HF incidences continues to increase. The current definition of HF restricts itself to stages at which clinical symptoms are apparent.
Kalmonovich, Eran   +11 more
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Frailty in Advanced Heart Failure

Heart Failure Clinics, 2016
Frailty is defined as a biological syndrome reflecting impaired physiologic reserve and heightened vulnerability to stressors. The evolving profile of heart failure (HF), increased survival of aging patients with complex comorbidities in parallel with the growing population undergoing mechanical circulatory support as lifetime therapy, means that ...
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Advanced Therapies for Advanced Heart Failure in Women

Heart Failure Clinics, 2019
Women with advanced heart failure (HF) are underrepresented in trials of short-term and durable mechanical circulatory support although they derive similar benefit. In acute HF, intensive medical and interventional therapies are effective but underutilized.
Marlena V, Habal   +2 more
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