CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Design and Verification of Multiphase Multilevel Traction Inverter
The paper presents the practical design and implementation of a three-level neutral point clamped (TNPC) six-phase inverter rated at 100 kVA. The study initiates with prior work review, whereby most research work done earlier was mainly simulation-based.
Patrik Resutík +2 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
ADVANCED 15-LEVEL INVERTER DESIGN FOR SOLAR PV INTEGRATION
A new 15 level inverter is presented in the paper to improve the solar photovoltaic (PV) grid integration process. Improved substantially in the pattern of waves quality with the current THD 3.91%, and voltage THD to 15.77%.
E. Parimalasundar +5 more
doaj +1 more source
ANN Controller Based Single phase Inverter in Smart City
Solar-grid integration is a method for incorporating large amounts of photovoltaic (PV) supply to the grid. Advanced inverter technology, smart grids technology, islanding detection technology, solar-grid forecasting technology, grid-plant protection ...
HyunHo Park
doaj
Design and Optimization of Multilevel Inverters for Enhanced Power Quality in Renewable Energy Applications [PDF]
Multilevel inverters have gained significant attention in renewable energy systems due to their ability to generate high-quality output voltages with reduced harmonic distortion and lower switching losses. These inverters are widely used in photovoltaic (
Yuvaraj S. +6 more
doaj +1 more source
Holding Dissapearance in RTD-based Quantizers [PDF]
Multiple-valued Logic (MVL) circuits are one of the most attractive applications of the Monostable-to-Multistable transition Logic (MML), and they are on the basis of advanced circuits for communications.
Avedillo, M. -J. +2 more
core +1 more source
A wideband CPW ring power combiner with low insertion loss and high port isolation [PDF]
In this paper we present a coplanar waveguide (CPW)-based ring power combiner that exhibits less than 0.8 dB insertion loss, better than 15 dB port match and higher than 22 dB isolation loss over the frequency range from 50 GHz to 100 GHz.
Cumming, D.R.S. +4 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Advanced Testing Chain Supporting the Validation of Smart Grid Systems and Technologies
New testing and development procedures and methods are needed to address topics like power system stability, operation and control in the context of grid integration of rapidly developing smart grid technologies.
Brandl, Ron +7 more
core +1 more source

