Results 201 to 210 of about 323,704 (343)

Paediatric developmental safety and the ICH E11A extrapolation of safety

British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Rebecca Racz, Sherbet Samuels, Dionna J. Green, Lynne P. Yao   +6 more
wiley   +1 more source

PKRxiv: A Best Practice Model for Advancing Pharmacoequity Through Open Pharmacokinetic Data Sharing

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development is increasingly integrated across the drug development continuum, enabling more efficient, cost‐effective, and targeted trials while reducing reliance on animal studies. Achieving pharmacoequity requires not only equitable access to medicines but also to the data and knowledge that inform drug development and regulatory ...
Shakir Atoyebi, Prajith Venkatasubramanian, Abdulafeez Akinloye, Oluwasegun Eniayewu, Brookie M. Best, Laura Else, Adeniyi Olagunju   +6 more
wiley   +1 more source

Amniocentesis Results According to Risk Factors: A Result of 1026 Women With Advanced Maternal Age

Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2016
Tuncay Yüce, Erkan Kalafat, Batuhan Özmen, Acar Koç, Feride Söylemez   +4 more
doaj   +1 more source

Preimplantation Genetic Testing for Aneuploidy Improves Clinical, Gestational, and Neonatal Outcomes in Advanced Maternal Age Patients Without Compromising Cumulative Live-Birth Rate.

, 2019
Laura Sacchi, Elena Albani, Amalia Cesana, Antonella Smeraldi, Valentina Parini, Marco Fabiani, Maurizio Poli, Antonio Capalbo, Paolo Emanuele Levi-Setti   +8 more
openalex   +2 more sources

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Delayed motherhood: Birth outcomes at extremely advanced maternal age: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Karabulut A, Kantarci S, Kantarci S, Dağli U, Atici E, İleri A, Engür D, Uygur Ö, Karataşli V.   +8 more
europepmc   +1 more source

Sudan at War With Itself: Civilian Devastation in the Civil War

Conflict Resolution Quarterly, EarlyView.
ABSTRACT A civil war is raging in Sudan between the Sudan Armed Forces (SAF) and the Rapid Support Forces (RSF) along with militia groups. Beginning on April 15, 2023, and continuing at least to this writing (October 15, 2025), civilian noncombatants have been subjected to bombings, beatings, torture, shootings, rape, and murder on a large scale. Since
Daniel Rothbart, Bayan Abubakr, Beltina Gjeloshi, Dieter Pfoser   +3 more
wiley   +1 more source

Maternal and perinatal outcomes in adolescents and women with advanced maternal age. [PDF]

Rev Saude Publica
Gama SGND, Schilithz AOC, Leal MDC, Carmo TTD, Theme-Filha MM, Barros DC, Soares GCF, Martinelli KG.   +7 more
europepmc   +1 more source

Advanced maternal age is a risk factor for both early-onset and late-onset hypertensive disorders of pregnancy: the Japan environment and children’s study

Kazuma Tagami, Noriyuki Iwama, Hirotaka Hamada, Hasumi Tomita, Natsumi Kumagai, Hongxin Wang, Seiya Izumi, Zen Watanabe, Mami Ishikuro, Taku Obara, Hirohito Metoki, Yuichiro Miura, Chiharu Ota, Shinichi Kuriyama, Takahiro Arima, Nobuo Yaegashi, Masatoshi Saito   +16 more
openalex   +1 more source

Ethyl Glucuronide in Hair: A 10‐Year Overview

Drug Testing and Analysis, EarlyView.
The present study builds on a unique collection of more than 68,000 hair EtG results collected in the Northen Italy between 2013 and 2022. We investigated trends in alcohol consumption in terms of age, gender, recidivism, applicants, sampling region, sampling length, across seasons, and the COVID‐19.
Sara Casati, Alessandro Ravelli, Roberta F. Bergamaschi, Caterina Fabbri, Erika Palmisano, Andrea Ostinelli, Gabriella Roda, Giuseppe Facchi, Marica Orioli   +8 more
wiley   +1 more source