Correction: Inhibition of ferroptosis counteracts the advanced maternal age-induced oocyte deterioration. [PDF]
Zeng W +12 more
europepmc +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Zishen Yutai Pill increased live births in advanced maternal age women: a randomized clinical trial. [PDF]
Li Y +13 more
europepmc +1 more source
The multiple hit model of infantile and epileptic spasms: The 2025 update
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou +6 more
wiley +1 more source
Perinatal outcomes in pregnancies with very and extremely advanced maternal age: An Italian multicenter retrospective cohort study. [PDF]
Ammar O +10 more
europepmc +1 more source
Ketogenic diet for infantile epileptic spasms
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
Advanced maternal age and risk perception
Advanced maternal age (AMA) is linked to several adverse pregnancy outcomes, hence these pregnancies are considered to be "high risk." Risk perception impacts pregnant women’s health care use, health behaviors, and adherence to medical recommendations. Yet, a gap remains in the understanding of perception of pregnancy risk and its contributing factors.
openaire +1 more source
Teacher‐Led Universal Eating Disorder Prevention Programmes in Schools: A Scoping Review
ABSTRACT Objective This scoping review seeks to evaluate the efficacy of teacher‐led interventions in mitigating risk factors related to eating disorders, considering the necessity for universal prevention programmes that can be effectively administered by educators.
Jessica Parker +3 more
wiley +1 more source
Influencing factors of pregnancy-related anxiety in advanced maternal age primigravidas and the development and evaluation of personalized psychological nursing interventions. [PDF]
Gao Y +5 more
europepmc +1 more source

