Results 221 to 230 of about 288,435 (354)

Delineation and monitoring of the T cell repertoire of adoptive cell transfer product during the treatment of advanced melanoma. [PDF]

Genome Med
Kerr C, Soleimani S, Mulder DT, Nabbi A, Gray D, Pedersen S, Sotov V, Sudhaman S, Nguyen L, Hirano N, Ohashi PS, Butler MO, Pugh TJ.   +12 more
europepmc   +1 more source

Electrochemotherapy for the Treatment of Unresectable Locoregionally Advanced Cutaneous Melanoma: A Systematic Review

, 2017
M.J. Aguado-Romeo, S. Benot-López, Antonio Romero-Tabares   +2 more
openalex   +1 more source

Table S4 from Safety, Efficacy, and Biomarker Analysis of Toripalimab in Previously Treated Advanced Melanoma: Results of the POLARIS-01 Multicenter Phase II Trial

, 2023
Bixia Tang, Zhihong Chi, Yingbo Chen, Xiufeng Liu, Di Wu, Jing Chen, Xin Song, Weifeng Wang, Lihou Dong, Haifeng Song, Wu Hai, Hui Feng, Sheng Yao, Shuikui Qin, Xiaoshi Zhang, Jun Guo   +15 more
openalex   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Antibiotic Exposure Does Not Impact Anti-BRAF/Anti-MEK Targeted Therapy Outcome in Patients with Advanced Melanoma. [PDF]

Curr Oncol
Wang YS, Wang QY, Moise AE, Syed HC, Malo J, Soberano S, Belkaid W, Messaoudene M, Bélanger K, Desilets A, Jamal R, Routy B, Elkrief A.   +12 more
europepmc   +1 more source

<p>Treatment of Advanced/Metastatic Melanoma in the United States and Western Europe: Results of the CancerMPact Survey</p>

, 2020
Stephanie Hawthorne, Linda Zhao, Madelyn Hanson, Gena Kanas, Christine Davis, David S. Robinson, Matthew Turnure, O Clark   +7 more
openalex   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Germline MC1R Variant Status and Efficacy of Immune Checkpoint Inhibitors in Patients With Advanced Melanoma. [PDF]

Pigment Cell Melanoma Res
Yang M, Brage SE, Lapins J, Grozman V, Svedman FC, Höiom V, Helgadottir H.   +6 more
europepmc   +1 more source

Supplementary Figure S2 from Neoantigen targetability in progressive advanced melanoma

Jitske van den Bulk, Els M.E. Verdegaal, Manon van der Ploeg, Marten Visser, Joana B. Nunes, Arnoud H. de Ru, Rayman T.N. Tjokrodirijo, Marieke E. Ijsselsteijn, Natasja I. Janssen, Ruud van der Breggen, Linda de Bruin, Pita de Kok, George M.C. Janssen, Dina Ruano, Ellen Kapiteijn, Peter A. van Veelen, Noel F.C.C. de Miranda, Sjoerd H. van der Burg   +17 more
openalex   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source