Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Real-time quantitative analysis of volatile products generated during solid-state polypropylene thermal oxidation [PDF]
Analysis of volatile organic compounds (VOCs) during PP thermal oxidation under three oxygen partial pressures (0%, 21% and 100% of atmospheric pressure) at 140 C was performed by proton transfer reaction coupled with Fourier transform ion cyclotron ...
LEPROVOST, Julien +6 more
core +1 more source
Application of advanced oxidation processes for effective Reactive Red 241 degradation
Advanced oxidation processes (AOPs) were investigated for the Reactive Red 241 (RR 241) degradation in aqueous solutions. Nine different methods were tested: the Fenton process, Fenton combined with Sodium Percarbonate (Fenton-SP), Fenton with MgO₂ ...
Barbara Pieczykolan +9 more
doaj +1 more source
A Graphite Cathode Modified by an Industrial Grade of Carbon Black for Assisting Electro-Fenton Technique: A Pesticide Wastewater Treatment [PDF]
In this study, an Electro-Fenton (EF) reaction was employed to treat hazardous and resistant wastewater from a pesticide factory using graphite cathode modified with industrial carbon black (N330).
Mohsen Mohammadi, Reza Davarnejad
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Applications of advanced oxidation processes: present and future
The use of advanced oxidation processes (AOPs) to remove pollutants in various water treatment applications has been the subject of study for around 30 years. Most of the available processes (Fenton reagent, O3 under basic conditions, O3/H2O2, O3/UV, O3/solid catalyst, H2O2/Mn+, H2O2/UV, photo-assisted Fenton, H2O2/solid catalyst, H2O2/NaClO, TiO2/UV ...
H, Suty, C, De Traversay, M, Cost
openaire +2 more sources
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Comparison Between the Efficiency of Advanced Oxidation Process and Coagulation for Removal Organophosphorus and Carbamat Pesticides [PDF]
Background and Objectives: Water pollution by pesticides has adverse effects on the environment and human health, as well .In recent years, advanced oxidation processes, have been gone through to a very high degree for pesticides removal.
A.R Rahmani, M.T Samadi, M Khodadadi
doaj

