Results 11 to 20 of about 8,764,093 (218)
Challenges for Economic Evaluations of Advanced Therapy Medicinal Products: A Systematic Review.
Value in Health, 2022 OBJECTIVES Advanced therapy medicinal products (ATMPs) are drugs for human use for the treatment of chronic, degenerative, or life-threatening diseases that are based on genes, tissues, or cells.
Antonio Olry de Labry-Lima +5 more
semanticscholar +1 more source
Value-based pricing for advanced therapy medicinal products: emerging affordability solutions
International Journal of Technology Assessment in Health Care, 2021 The emergence of advanced therapy medicinal products (ATMPs), a disruptive class of health technologies, is generating important challenges in terms of value assessment and their high prices introduce critical access and affordability concerns.
Elisabete Gonçalves
semanticscholar +1 more source
Advanced Therapy Medicinal Products for the Eye: Definitions and Regulatory Framework
Pharmaceutics, 2021 Advanced therapy medicinal products (ATMPs) are a group of innovative and complex biological products for human use that comprises somatic cell therapy medicinal products, tissue engineered products, gene therapy medicinal products, and the so-called ...
Marina López-Paniagua +5 more
semanticscholar +1 more source
Is the Conjunctiva a Potential Target for Advanced Therapy Medicinal Products?
Pharmaceutics, 2021 The conjunctiva is a complex ocular tissue that provides mechanical, sensory, and immune protection for the ocular surface. It is affected by many diseases through different pathological mechanisms.
Y. Diebold, Laura García-Posadas
semanticscholar +1 more source
International Journal of Molecular Sciences, 2021 Temporomandibular joint osteoarthritis (TMJ-OA) is a chronic degenerative disease that is often characterized by progressive impairment of the temporomandibular functional unit.
R. Köhnke +11 more
semanticscholar +1 more source
Advanced therapy medicinal products development - from guidelines to medicines in the market.
Biotechnology AdvancesIn Europe, Advanced Therapy Medicinal Products (ATMPs) include medicines based on gene therapy, somatic-cell therapy, tissue-engineered products, and combined ATMPs.
C. Frederico +3 more
semanticscholar +1 more source
The issue of heterogeneity of MSC-based advanced therapy medicinal products–a review
Frontiers in Cell and Developmental BiologyMesenchymal stromal stem cells (MSCs) possess a remarkable potential for numerous clinical applications due to their unique properties including self-renewal, immunomodulation, paracrine actions and multilineage differentiation.
Ana Bajc Česnik, U. Švajger
semanticscholar +1 more source
International Journal of Molecular Sciences, 2020 Stromal vascular fraction (SVF) containing adipose stem cells (ASCs) has been used for many years in regenerative plastic surgery for autologous applications, without any focus on their potential allogenic role.
P. Gentile +6 more
semanticscholar +1 more source
Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products
International Journal of Molecular SciencesExtracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and therapeutic modalities. This paper describes major GMP-based upstream and downstream manufacturing processes for EV large-scale production, also focusing on ...
A. Stawarska +6 more
semanticscholar +1 more source
Academic challenges on advanced therapy medicinal products' development: a regulatory perspective.
CytotherapyAdvanced therapy medicinal products (ATMPs) are becoming the new kid on the block for the treatment of a variety of indications with promising results.
Eulàlia Olesti +7 more
semanticscholar +1 more source