Results 131 to 140 of about 455,707 (344)

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source

Enhancing Security and Privacy in IoT Data Streams: Real-Time Anomaly Detection for Threat Mitigation in Traffic Management

Computer Sciences & Mathematics Forum
The rapid expansion of IoT in smart cities has improved traffic management but increased security risks. Traditional IDS struggle with advanced threats, prompting adaptive solutions.
Oumayma Berraadi, Hicham Gibet Tani, Mohamed Ben Ahmed   +2 more
doaj   +1 more source

Delayformer: Spatiotemporal Transformation for Predicting High‐Dimensional Dynamics

Advanced Science, EarlyView.
Delayformer introduces a multivariate spatiotemporal transformation (mvSTI) that converts observed variables into delay‐embedded states and cross‐learns their dynamics using a shared Vision Transformer encoder. This approach, grounded in dynamical systems theory, simultaneously predicts all variables in high‐dimensional systems, outperforming state‐of ...
Zijian Wang, Peng Tao, Luonan Chen
wiley   +1 more source

Real-Time Traffic Insights With Physics-Informed Neural Networks: Integrating the Aw-Rascle Model and LLMs

IEEE Access
Traffic congestion and inefficiencies in transportation networks pose significant challenges to road safety, travel times, and environmental sustainability. Traditional traffic management systems, typically reliant on sparse sensor data and rigid models,
Tewodros Syum Gebre, Simachew Endale Ashebir, Jeffrey Blay, Matilda Anokye, Venktesh Pandey, Leila Hashemi-Beni   +5 more
doaj   +1 more source

Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies

Advanced Science, EarlyView.
This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang, Hao Zheng, Zi‐Chang Liu, Ling‐Jie Luo, Xiao Dong, Xin‐Gang Cui, Yan‐Wei Wu, Liang Chen   +7 more
wiley   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Introduction to Security Onion [PDF]

, 2016
Security Onion is a Network Security Manager (NSM) platform that provides multiple Intrusion Detection Systems (IDS) including Host IDS (HIDS) and Network IDS (NIDS). Many types of data can be acquired using Security Onion for analysis.
Heenan, Ross, Moradpoor, Naghmeh
core  

Intelligent Sensing: The Emerging Integration of Machine Learning and Soft Sensors Based on Hydrogels and Ionogels

Advanced Science, EarlyView.
By integrating with machine learning (ML), hydrogel‐ and ionogel‐based soft sensors are gaining human brain‐like capabilities to perceive, learn, and predict. This review summarizes their advances, focusing on ML‐powered applications such as handwriting/gesture/object/motion/speech recognition, health monitoring, food detection, and beyond.
Wenqing He, Rumin Lin, Suixiu Kong, Mengyi Qiang, Lingqi Huang, Bing Dai, Xi Yao, Lei Su, Xueji Zhang   +8 more
wiley   +1 more source

Bioinspired Oxygen‑Enriched Nanodiamonds as Electrolytic Erythrocyte Mimics for Dendrite‑Free Zinc‑Ion Batteries

Advanced Science, EarlyView.
Inspired by the cyclic transport of oxygen from the lungs (high‑O2 region) to tissues (low‑O2 region), oxygen‑enriched nanodiamond (OND) is introduced into aqueous zinc‑ion batteries as “electrolyte erythrocytes.” These OND repeatedly shuttle Zn2+ from high‑ to low‑concentration regions, dramatically flattening the Zn2+ gradient and thereby effectively
Wenhao Ding, Wuxin Bai, Zhenjie Lu, Xiangjie Guo, Zhen Wu, Jingwen Sun, Pan Xiong, Wenyao Zhang, Xiaoping Ouyang, Xin Wang, Junwu Zhu, Yongsheng Fu   +11 more
wiley   +1 more source

Ferroelectric HZO Thin Films for FEFETs: Crystal Structure‐Device Performance Relationship

Advanced Electronic Materials, EarlyView.
Crystal Structure of HZO Thin Films Methods of Thin Film Deposition 1T‐FeFET Design Influence on Ferroelectric Properties FeFET Applications Recent Advances and Challenges ORTHORHOMBIC HEARTBEAT. Abstract The rapid development of hafnium zirconium oxide (HZO) thin films has established ferroelectric field‐effect transistors (FeFETs) as strong ...
Harsha Ragini Aturi, Ramana Murthy Gajula, Deepshikha Rathore   +2 more
wiley   +1 more source