Results 211 to 220 of about 455,707 (344)

Exploring the Profile of Online Gamblers: Key Factors and the Role of Smartphone Addiction in Long‐Term Gambling Engagement

open access: yesJournal of Consumer Behaviour, EarlyView.
ABSTRACT The rapid expansion of online gambling has significantly impacted the gambling industry. However, concerns have arisen regarding how psychosocial factors and excessive smartphone use influence user behavior on online gambling platforms, which has highlighted the need for broader and long‐term studies. More nationally representative studies are
Hazal Dilan Erdem   +2 more
wiley   +1 more source

ARC Expands the DAAM1 Microexon‐Mediated Actin–RHOA/ROCK Interplay

open access: yesCytoskeleton, EarlyView.
ABSTRACT Actin cytoskeleton and its dynamics play a crucial role in synaptic function, influencing dendritic spines' structural and functional plasticity. Recent findings unveiled the significance of alternative splicing of a neural‐specific microexon in DAAM1 in modulating actin's role in synaptic processes.
Patryk Poliński   +2 more
wiley   +1 more source

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang   +17 more
wiley   +1 more source

Foundational Principles for the Quantitative Translation of T‐Cell Therapeutics for Hematologic Malignancies and Immunology

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
T‐cell engaging antibodies (TCEs) and chimeric antigen receptor (CAR) T cells (CAR‐T cells) are among precision medicine therapies that have revolutionized the treatment of hematologic cancers. Their success in oncology has piqued interest in translating this promise into additional indications, such as autoimmune disorders.
Peter Ashcroft   +6 more
wiley   +1 more source

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