Expanding Hereditary Spastic Paraplegias Limits: Biallelic SPAST Variants in Cerebral Palsy Mimics
ABSTRACT Objective Hereditary spastic paraplegias (HSP) are rare neurodegenerative disorders marked by spasticity and lower limb weakness. The most common type, SPG4, is usually autosomal dominant and caused by SPAST gene variants, typically presenting as pure HSP.
Gregorio A. Nolasco +18 more
wiley +1 more source
Prototyping a graph-based approach for efficient vehicle tracking in a cluster controlled CCTV surveillance systems [PDF]
In this work, an advanced multimodal video summarization system is developed for a clustercontrolled traffic surveillance environment. Addressing the growing challenges of vehicle density and traffic complexity, the system employs state-of-the-art deep ...
Apurva NARAYAN +3 more
doaj +1 more source
Factors Influencing the Decisions and Actions of Pilots and Air Traffic Controllers in Three Plausible NextGen Environments [PDF]
In the current air traffic management (ATM) system, pilots and air traffic controllers have well-established roles and responsibilities: pilots fly aircraft and are concerned with energy management, fuel efficiency, and passenger comfort; controllers ...
Battiste, Vernol +3 more
core +1 more source
Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam +6 more
wiley +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
Traffic Flow Optimization at Toll Plaza Using Proactive Deep Learning Strategies
Global urbanization and increasing traffic volume have intensified traffic congestion throughout transportation infrastructure, particularly at toll plazas, highlighting the critical need to implement proactive transportation infrastructure solutions ...
Habib Talha Hashmi +5 more
doaj +1 more source
Advances in Micro/Nanofiber‐Based Porous Materials for High‐Performance Thermal Insulation
Micro/nanofiber porous materials have engendered great interest in the thermal insulation field. Herein, the structural designs, fabrication techniques, and applications of the micro/nanofiber thermal insulation materials are systematically summarized.
Xiaobao Gong +5 more
wiley +1 more source
“Charge while driving” for electric vehicles: road traffic modeling and energy assessment
The aim of this research study is to present a method for analyzing the performance of the wireless inductive charge-while-driving (CWD) electric vehicles, from both traffic and energy points of view.
Francesco Paolo Deflorio +3 more
doaj +1 more source
This study developed and verified a travel speed prediction model based on the travel speed and work zone statistics collected from the advanced traffic management system (ATMS) real-time data in Daegu, South Korea. A clustered K-nearest neighbors (CKNN)
Hyun Su Park +3 more
doaj +1 more source
Vehicle Localization Kalman Filtering for Traffic Light Advisor Application in Urban Scenarios
The recent advancements in Intelligent Transportation Systems (ITS) have revealed significant potential for enhancing traffic management through Advanced Driver Assist Systems (ADASs), with benefits for both safety and environment.
Daniele Vignarca +2 more
doaj +1 more source

