Results 71 to 80 of about 1,780,773 (236)

Do Internal Capabilities Affect Competitive Advantage? The Case of a Regional Owned Company

Jurnal Economia
This research aims to get an overview of the factors affecting organizational competitive advantage and to obtain insights into the most influential factors concerning organizational competitive advantage.
Anita Maharani, Tammy Kathlia Kartasunjaya   +1 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Progress in gasless endoscopic thyroidectomy

Frontiers in Endocrinology
Gasless endoscopic thyroidectomy obviates the necessity for carbon dioxide insufflation to establish a surgical workspace, thus mitigating the potential complications associated with this practice.
Xianbin Cheng, Xiangfu Ding, Sijia Wang, Siyu Li, Hong Zhang   +4 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Relationship Between Virtual Pharmacology Lecture, Attendance and Performance: Personal Experience With Veterinary Students of the University of BUEA, Southwest Cameroon

Pharmacology Research & Perspectives
Risk and cost of transportation and other unforeseen circumstances can hamper in‐person pharmacology lectures with students. Hence, the study is aimed at identifying the advantages and disadvantages of pharmacology lectures via Zoom.
Saganuwan Alhaji Saganuwan, Manchang Tanyi Kingsley   +1 more
doaj   +1 more source

A Review on Pulsed Laser Preparation of Quantum Dots in Colloids for the Optimization of Perovskite Solar Cells: Advantages, Challenges, and Prospects

Nanomaterials
In recent years, academic research on perovskite solar cells (PSCs) has attracted remarkable attention, and one of the most crucial issues is promoting the power conversion efficiency (PCE) and operational stability of PSCs.
Liang Sun, Yang Li, Jiujiang Yan, Wei Xu, Liangfen Xiao, Zhong Zheng, Ke Liu, Zhijie Huang, Shuhan Li   +8 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Comparative Advantage of Digital and Face-to-Face Data Collection in 21st-Century Research: Evidence from Agricultural Research

Torkwase Journal of Agricultural Research
Objective: The aim of this study was to determine the comparative advantages of digital media and face-to-face in data collection. Methods: The researcher used the descriptive survey research design.
Verlumun Celestine Gever
doaj   +1 more source