Results 191 to 200 of about 4,112,704 (245)

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

open access: yesSmart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan   +5 more
wiley   +1 more source

Insect succession patterns on pig carrion in southern Nigeria. [PDF]

open access: yesForensic Sci Med Pathol
Etoniru IS   +4 more
europepmc   +1 more source

How We Simulate Nanopores

open access: yesSmall Methods, EarlyView.
Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz   +5 more
wiley   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

open access: yesVIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding   +10 more
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

open access: yesVIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf   +5 more
wiley   +1 more source

How weather got its words: a history of meteorological English – Part 2: the scientific age and beyond

open access: yesWeather, EarlyView.
The English language is a gargantuan, gluttonous beast. It has become extraordinary in its powers of assimilation – such that we rarely consider the origins of the words we use. In this paper, we will shed light on these origins, including the Pontic–Caspian steppe, the British Empire and, of course, a TV show.
Kieran M. R. Hunt
wiley   +1 more source

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