Results 91 to 100 of about 149,065 (306)

What is the epidemiology of medication errors, error-related adverse events and risk factors for errors in adults managed in community care contexts? A systematic review of the international literature [PDF]

, 2018
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.Objective To investigate the epidemiology of medication errors and ...
Aljadhey, Hisham, Aloudah, Nouf, Assiri, Ghadah, Grant, Elizabeth, Mahmoud, Mansour, Shebl, Nada, Sheikh, Aziz   +6 more
core   +3 more sources

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Evolução e elementos-chave do sistema de farmacovigilância do Brasil: uma revisão de escopo a partir da criação da Agência Nacional de Vigilância Sanitária

Cadernos de Saúde Pública, 2018
Esta revisão de escopo objetiva descrever e caracterizar o sistema de farmacovigilância do Brasil (SINAF) e averiguar o atendimento aos requisitos mínimos propostos pela Organização Mundial da Saúde para um desempenho funcional de sistemas nacionais ...
Daniel Marques Mota, Álvaro Vigo, Ricardo de Souza Kuchenbecker   +2 more
doaj   +1 more source

A Critical Examination of the FDA’s Efforts to Preempt Failure-to-Warn Claims [PDF]

, 2007
This article explores the legality and wisdom of the FDA’s effort to persuade courts to find most failure-to-warn claims preempted. The article first analyzes the FDA’s justifications for reversing its long-held views to the contrary and explains why ...
Kessler, David A., Vladeck, David C.
core   +1 more source

Applying the trigger review method after a brief educational intervention: potential for teaching and improving safety in GP specialty training? [PDF]

, 2013
<p>Background: The Trigger Review Method (TRM) is a structured approach to screening clinical records for undetected patient safety incidents (PSIs) and identifying learning and improvement opportunities.
Academy of Royal Medical Colleges, Royal College of Surgeons of Edinburgh and the NHS Institute for Innovation and Improvement, C de Wet, C De Wet, Carl de Wet, DLM Zwart, FA Griffin, General Medical Council, H Jaques, J McKay, J McKay, John McKay, M Woloshynowych, Moya Kelly, P Bowie, P Bowie, Paul Bowie, Royal College of General Practitioners. RCGP Curriculum 2010, Statement 2.02, S Executive, TA Apekey, The Scottish Government, World Health Organization   +20 more
core   +1 more source

Temporal Trends and Short‐ and Long‐Term Mortality of People With Acute Myocardial Infarction and Rheumatoid Arthritis: A Nationwide Cohort Study

Arthritis Care &Research, EarlyView.
Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler, Nicholas Weight, Muhammad Rashid, Rodrigo Bagur, Purvi Parwani, Samantha Hider, Edward Roddy, Robert Butler, Mamas A. Mamas   +8 more
wiley   +1 more source

Harvesting the Promise of AOPs: An assessment and recommendations [PDF]

, 2018
The Adverse Outcome Pathway (AOP) concept is a knowledge assembly and communication tool to facilitate the transparent translation of mechanistic information into outcomes meaningful to the regulatory assessment of chemicals.
Ankley, Gerald T., Carusi, Annamaria, Davies, Mark R., De Grandis, Giovanni De, Escher, Beate I., Hodges, Geoff, Wheelan, Maurice, Willet, Catherine, Y. Leung, Kenneth M.   +8 more
core   +4 more sources

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs

BMC Bioinformatics, 2011
Background The identification of drug characteristics is a clinically important task, but it requires much expert knowledge and consumes substantial resources.
Tsafnat Guy, Polasek Thomas M, Anthony Stephen, Lin Frank PY, Doogue Matthew P   +4 more
doaj   +1 more source

Disrupting the Path from Childhood Trauma to Juvenile Justice: An Upstream Health and Justice Approach [PDF]

, 2016
A groundbreaking public health study funded by the U.S. Centers for Disease Control and Prevention (CDC) and the Kaiser Foundation found astoundingly high rates of childhood trauma, including experiences like abuse, neglect, parental substance abuse ...
Cannon, Yael, Hsi, Andrew
core   +2 more sources