Safety evaluation of baloxavir marboxil: analysis and discussion utilizing real adverse events from the FAERS database. [PDF]
Lai X+6 more
europepmc +1 more source
Analysis of adverse drug reactions of Denosumab (Prolia) in osteoporosis based on FDA adverse event reporting system (FAERS) [PDF]
Ruibo Li+4 more
openalex +1 more source
The article presents the development of artificial lipid droplets (aLDs) as biomimetic nanocarriers to enhance intramuscular fat (IMF) content in pigs. These aLDs, loaded with oleic acid, significantly increase IMF by up to 35% in muscle tissues without adverse side effects. This innovative approach improves pork quality by enhancing marbling, offering
Pengxiang Zhao+8 more
wiley +1 more source
Enhancing medication error reporting through interprofessional education: analysis of Medwatch reporting accuracy and completion rates between teams and individuals. [PDF]
Saad AH+6 more
europepmc +1 more source
Exosome‐based nanoparticles (GC‐Exo‐CD16Ab) are designed to deliver glucocorticoids (GC) specifically to decidual CD16+ NK cells and macrophages. This targeted delivery effectively suppresses the cytotoxicity of decidual NK cells, inhibits M1 macrophage polarization, and modulates the decidual microenvironment.
Linlin Wang+17 more
wiley +1 more source
Disproportionality analysis of drug-induced erectile dysfunction using FAERS database. [PDF]
Tian X+7 more
europepmc +1 more source
Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou+8 more
wiley +1 more source
Comparison of ileus risk in selected second-generation antipsychotics based on FAERS database. [PDF]
Tan Y, Xia H, Song Q.
europepmc +1 more source
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen+12 more
wiley +1 more source
Global pharmacovigilance reporting of the first monoclonal antibody for canine osteoarthritis: a case study with bedinvetmab (Librela™). [PDF]
Monteiro BP+7 more
europepmc +1 more source