Results 291 to 300 of about 976,952 (369)

PMC18 COMPARISONS OF DATA MINING ALGORITHMS FOR ADVERSE DRUG REACTIONS: AN EMPIRICAL STUDY BASED ONTHE ADVERSE EVENT REPORTING SYSTEM OFTHE FOOD AND DRUG ADMINISTRATION

, 2008
Y Chen, JJ Guo, NC Patel, M. Steinbuch, XD Lin, C. Ralph Buncher   +5 more
openalex   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

PHP27 USING COLLABORATIVE PROGRAM BETWEEN PHARMACISTS AND NURSES YO IMPROVE SPONTANEOUS ADVERSE DRUG REACTION REPORTING SYSTEM IN THAILAND

, 2010
Nantaya Prakongsai, Manus Pongchaidecha
openalex   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Adverse drug reaction assessment of pembrolizumab in cervical cancer treatment: a real-world pharmacovigilance study using the FAERS database. [PDF]

Front Immunol
Zhang H, Zhou Z, Wang J, Wang S, Ren J, Zhang M, Yang M.   +6 more
europepmc   +1 more source

Quantitative Evaluation of Initial Symptoms as Predictors to Detect Adverse Drug Reactions Using Bayes’ Theory: Expansion and Evaluation of Drug-Adverse Drug Reaction–Initial Symptom Combinations Using Adverse Event Reporting System Database

, 2013
Daisuke Kobayashi, Shigeru Hosaka, Emiko Inoue, Kimie Ohshima, Nobuaki Kutsuma, Shinji Oshima, Yasushi Okuno   +6 more
openalex   +2 more sources

Rational Design of Inner Ear Drug Delivery Systems

Advanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu, Zhiyan Xuan, Haoyu Ren, Keng Chen, Hui Zhang, Huan Wang   +5 more
wiley   +1 more source

Analysis of Reporting Trends of Serious Adverse Events Associated With Anti-Obesity Drugs. [PDF]

Pharmacol Res Perspect
Raičević BB, Belančić A, Mirković N, Janković SM.   +3 more
europepmc   +1 more source

Advances in Electrical Materials for Bone and Cartilage Regeneration: Developments, Challenges, and Perspectives

Advanced Science, EarlyView.
This review explores the challenges of treating bone and cartilage defects, emphasizing the role of endogenous electric fields in bone and cartilage regeneration. It highlights recent advancements in electroactive biomaterials, including nanogenerators, piezoelectric materials, triboelectric scaffold, and zwitterionic hydrogels.
Yubin Yao, Xi Cui, Shenglong Ding, Ketao Wang, Mingzhu Zhang   +4 more
wiley   +1 more source

Characteristic analysis of adverse reactions of histone deacetylase inhibitors based on WHO-VigiAccess. [PDF]

Front Pharmacol
Yin T, Liu Y, Li C, Feng X, Lin Y, Qu Z.
europepmc   +1 more source