Integrating Pharmacogenomics and Network Topology for Machine Learning Prediction of HLA-Associated Severe Cutaneous Adverse Drug Reactions. [PDF]
Ponduan T +5 more
europepmc +1 more source
From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Assessment of adverse drug reactions encountered in primary care settings. [PDF]
Ko KD.
europepmc +1 more source
The transition from cryogenic distillation to polymeric sorbents for light hydrocarbon purification is crucial for energy and environmental sustainability. The polymeric sorbents are engineered to separate gas mixtures based on their specific properties.
Kelechi Festus +9 more
wiley +1 more source
Determinants and outcomes of adverse drug reactions among people living with HIV on antiretroviral therapy in Nigeria. [PDF]
Etuk VP +3 more
europepmc +1 more source
Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi +13 more
wiley +1 more source
The fibrosis-plasticity axis (FPA) and ionic resilience: a systems framework for understanding adverse drug reactions in ageing populations. [PDF]
Carballo A.
europepmc +1 more source
The incidence of adverse reactions to drugs [PDF]
openaire +3 more sources
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda +2 more
wiley +1 more source
Severe cutaneous adverse drug reactions due to antituberculosis drugs and their management. [PDF]
Keren M +5 more
europepmc +1 more source

