Results 1 to 10 of about 17,686,029 (257)

Pilot Study to Assess Outcomes of a Drug Allergy Clarification Service on a General Medicine Floor at a Local Community Hospital

INNOVATIONS in Pharmacy, 2018
Purpose: Drug allergy documentation in the patient medical record varies in level of detail, and drug intolerances are often inappropriately documented as an allergy in the medical record. A pilot study was conducted to determine the impact of a pharmacy-
Crystal Deas, C. Whitney White
doaj   +1 more source

Safety and Efficacy of Chimeric Antigen Receptor T-Cell Therapy for Glioblastoma: A Systemic Review and Meta-Analysis

Frontiers in Oncology, 2022
BackgroundChimeric antigen receptor (CAR) T-cell therapy is a promising treatment option for patients with refractory hematological malignancies. However, its efficacy in glioblastoma remains unclear.
Jong Keon Jang, Junhee Pyo, Chong Hyun Suh, Hye Sun Park, Hye Sun Park, Young Kwang Chae, Kyung Won Kim   +6 more
doaj   +1 more source

A Dose Escalation Study of Trientine Plus Carboplatin and Pegylated Liposomal Doxorubicin in Women With a First Relapse of Epithelial Ovarian, Tubal, and Peritoneal Cancer Within 12 Months After Platinum-Based Chemotherapy

Frontiers in Oncology, 2019
Background: Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related deaths worldwide. Preclinical studies found that copper-lowering agents could re-sensitize platinum-resistant cancer cells by enhancing the human copper ...
Yu-Fang Huang, Macus Tien Kuo, Yi-Sheng Liu, Ya-Min Cheng, Pei-Ying Wu, Cheng-Yang Chou   +5 more
doaj   +1 more source

Sorafenib-Induced Interstitial Pneumonitis in a Patient with Hepatocellular Carcinoma: A Case Report

Gut and Liver, 2010
Sorafenib is an oral multikinase inhibitor that has shown a survival benefit in patients with advanced hepatocellular carcinoma, and is considered to be generally safe.
doaj   +1 more source

On Perception and Consciousness in HPPD: A Systematic Review

Frontiers in Neuroscience, 2021
Hallucinogen-persisting perception disorder (HPPD) features as a diagnostic category in the DSM-5, ICD-11, and other major classifications, but our knowledge of the phenomenology of the perceptual symptoms involved and the changes in consciousness during
Pieter J. Vis, Pieter J. Vis, Pieter J. Vis, Anneke E. Goudriaan, Anneke E. Goudriaan, Bastiaan C. ter Meulen, Jan Dirk Blom, Jan Dirk Blom, Jan Dirk Blom   +8 more
doaj   +1 more source

Polymyxin B-Based Regimens for Patients Infected with Carbapenem-Resistant Gram-Negative Bacteria: Clinical and Microbiological Efficacy, Mortality, and Safety

Infection and Drug Resistance, 2022
Jian Qu,1,2 Ting-Ting Qi,1,2 Qiang Qu,3,4 Wen-Ming Long,5 Ying Chen,6 Yue Luo,7 Ying Wang1,2 1Department of Pharmacy, The Second Xiangya Hospital, Central South University, Changsha, 410011, People’s Republic of China; 2Institute of Clinical Pharmacy ...
Qu J, Qi TT, Qu Q, Long WM, Chen Y, Luo Y, Wang Y   +6 more
doaj  

Levetiracetam in clinical practice: efficacy and tolerability in epilepsy. [PDF]

, 2010
BACKGROUND: The aim of this study was to evaluate efficacy and tolerability of levetiracetam (LEV) in patients with different epilepsy syndromes. METHODS: We evaluated epileptic patients seen in the previous 18 months, including all patients with present
BILO, LEONILDA, de Leva MF, Meo R.
core   +1 more source

Synergistic and low adverse effect cancer immunotherapy by immunogenic chemotherapy and locally expressed PD-L1 trap

Nature Communications, 2018
Although great success has been obtained in the clinic, the current immune checkpoint inhibitors still face two challenging problems: low response rate and immune-related adverse effects (irAEs). Here we report the combination of immunogenic chemotherapy
Wantong Song, Limei Shen, Ying Wang, Qi Liu, Tyler J. Goodwin, Jingjing Li, Olekasandra Dorosheva, Tianzhou Liu, Rihe Liu, Leaf Huang   +9 more
semanticscholar   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

Utility of In Vitro Bioactivity as a Lower Bound Estimate of In Vivo Adverse Effect Levels and in Risk-Based Prioritization.

Toxicological Sciences, 2019
Use of high-throughput, in vitro bioactivity data in setting a point-of-departure (POD) has the potential to accelerate the pace of human health safety evaluation by informing screening level assessments. The primary objective of this work was to compare
K. Paul Friedman, M. Gagne, L. Loo, P. Karamertzanis, T. Netzeva, T. Sobański, Jill A. Franzosa, A. Richard, Ryan R. Lougee, A. Gissi, J. J. Lee, M. Angrish, J. Dorne, S. Foster, K. Raffaele, T. Bahadori, M. Gwinn, J. Lambert, M. Whelan, M. Rasenberg, T. Barton-Maclaren, Russell S. Thomas   +21 more
semanticscholar   +1 more source