Results 211 to 220 of about 1,393,863 (317)

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

open access: yesAdvanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham   +9 more
wiley   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer   +10 more
wiley   +1 more source

Atomic Size Misfit for Electrocatalytic Small Molecule Activation

open access: yesAdvanced Functional Materials, EarlyView.
This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong   +3 more
wiley   +1 more source

Comparison of Adverse Effect Profiles of Nafcillin and Oxacillin in Pediatric Patients. [PDF]

open access: yesJ Pediatr Pharmacol Ther
Warring SR   +3 more
europepmc   +1 more source

Self‐Powered Real‐Time Temperature Sensing Based on Flexible Ionic Elastomer on Triboelectric Nanogenerators

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a self‐powered real‐time ionic TENG temperature sensing system for flexible thermal management with high and real‐time temperature monitoring. Ionic liquids and elastomer chains are investigated under temperature via electrochemical and physical analysis, resulting in enhancing thermal sensitivity and output performance on TENG ...
Hee Jae Hwang   +9 more
wiley   +1 more source

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