Results 331 to 340 of about 5,734,618 (390)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Melasma secondary to drugs: a real-world pharmacovigilance study of the FDA adverse event reporting system (FAERS). [PDF]

BMC Pharmacol Toxicol
Qu Y, Wang S, Xie H, Meng X, Cui B, Xiao Z.   +5 more
europepmc   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Drug-induced pancreatitis: a real-world analysis of the FDA Adverse Event Reporting System and network pharmacology. [PDF]

Front Pharmacol
Xie H, Jiang L, Peng J, Hu H, Han M, Zhao B.   +5 more
europepmc   +1 more source

Vaccine Adverse Events and Adverse Reactions

Kansenshogaku Zasshi, 2019
openaire   +2 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

A pharmacovigilance study of olanzapine/samidorphan based on FDA Adverse Event Reporting System (FAERS). [PDF]

BMC Pharmacol Toxicol
He L, Shen M, Zhang L, Li Y, Li H.
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Real-World pharmacovigilance analysis of drug-related conjunctivitis using the FDA adverse event reporting system database. [PDF]

Sci Rep
Li X, Sun YQ, Liu MM, Tang JF.
europepmc   +1 more source