Results 91 to 100 of about 476,894 (337)

Ophthalmic corticosteroids-related adverse events: the FDA adverse event reporting system (FAERS) database pharmacovigilance study

Frontiers in Pharmacology
BackgroundCorticosteroids are extensively used in ophthalmology, particularly for treating various inflammatory conditions. Despite their effectiveness, prolonged or high-dose corticosteroid use is associated with significant adverse drug reactions (ADRs)
Chengzhi Liu, Xinyu Wang, Xusheng Cao
doaj   +1 more source

Drug Safety Monitoring in Children: Performance of Signal Detection Algorithms and Impact of Age Stratification [PDF]

, 2016
Introduction: Spontaneous reports of suspected adverse drug reactions (ADRs) can be analyzed to yield additional drug safety evidence for the pediatric population.
Dodd, C.N. (Caitlin), Kaguelidou, F. (Florentia), Osokogu, O.U. (Osemeke), Păcurariu, A.C. (Alexandra), Sturkenboom, M.C.J.M. (Miriam), Weibel, D.M. (Daniel)   +5 more
core   +3 more sources

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source

Age-stratified analysis of adverse event signals for clarithromycin: a disproportionality analysis using the FDA Adverse Event Reporting System

Therapeutic Advances in Drug Safety
Background: Clarithromycin is a widely used antibiotic, but its safety profile, particularly in different age groups, remains inadequately explored. Objectives: This study aims to characterize and illustrate the features of clarithromycin-related adverse
Haiyan Mai, Zhenpo Zhang, Yankun Liang, Jingping Zheng, Ling Su   +4 more
doaj   +1 more source

Otorhinolaryngologic complications after COVID-19 vaccination, vaccine adverse event reporting system (VAERS)

Frontiers in Public Health
BackgroundThere have been reports of otolaryngological adverse event following immunization (AEFI) such as instances of olfactory and gustatory dysfunction following COVID-19 vaccination.
Jieun Shin, Jieun Shin, Sung Ryul Shim, Sung Ryul Shim, Jaekwang Lee, Hyon Shik Ryu, Jong-Yeup Kim, Jong-Yeup Kim, Jong-Yeup Kim   +8 more
doaj   +1 more source

Vaccine [PDF]

BackgroundIn March 2009, the U.S. Food and Drug Administration licensed an inactivated, Vero cell culture-derived Japanese encephalitis vaccine (JE-VC [Ixiaro]) for use in adults. The vaccine was licensed based on clinical trial safety data in 3558 JE-VC

core  

Fosfomycin-associated adverse events: A disproportionality analysis of the FDA Adverse Event Reporting System

Drug Discoveries & Therapeutics
Fosfomycin, with its unique mechanism of action, has emerged as a promising option for clinicians to combat antimicrobial resistance and the limited availability of effective drugs, which has led to an increase in associated adverse events (AEs). This study aims to explore the AEs caused by fosfomycin through data mining of the US FDA Adverse Event ...
Luxuan, Yang, Wenyong, Zhang, Xiujuan, Shen, Meiqin, Liu, Meiying, Wu, Dan, Xiao   +5 more
openaire   +2 more sources

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He, Jie Wu, Chaonan Fan, Zheng Li, Jun Liu, Kechun Li, Quan Wang, Suyun Qian   +7 more
wiley   +1 more source

Vonoprazan-associated infection: an analysis of the Japanese Adverse Drug Event Report and the FDA Adverse Event Reporting System

Therapeutic Advances in Drug Safety
Background: Prolonged or excessive use of acid suppressants may increase the risk of Clostridioides difficile infection (CDI) by altering the intestinal microecosystem.
Mengling Ouyang, Shupeng Zou, Qian Cheng, Xuan Shi, Yazheng Zhao, Minghui Sun   +5 more
doaj   +1 more source

Signal mining of adverse events of proteasome inhibitors in multiple myeloma based on FAERS

Frontiers in Pharmacology
ObjectiveTo mine and analyze adverse events (AEs) related to proteasome inhibitors in multiple myeloma based on the FDA Adverse Event Reporting System (FAERS), providing references for rational clinical medication.MethodsAE data related to multiple ...
Yuan Peng, Yuan Peng, Yuying Zhou, Kaisen Shu, Xu Jia, Yan Zhong   +5 more
doaj   +1 more source