Results 171 to 180 of about 278,304 (313)

Fenfluramine in SCN1A‐related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability

Epilepsia Open, EarlyView.
Abstract The SCN1A gene is implicated in a broad spectrum of epilepsy phenotypes, ranging from self‐limited genetic epilepsy with febrile seizures plus (GEFS+) to severe developmental and epileptic encephalopathies such as Dravet syndrome (DS). While fenfluramine (FFA) has demonstrated strong efficacy in DS, its role in SCN1A‐related epilepsies beyond ...
Giovanni B. Dell'Isola, Alice Muda, Lucio Giordano, Renzo Guerrini, Alessandra Boncristiano, Nicola Pietrafusa, Maria Polselli, Francesca Bisulli, Francesca Ragona, Antonella Riva, Pasquale Striano, Domenica Immacolata Battaglia, Federico Vigevano   +12 more
wiley   +1 more source

Parental and Peer Relationships and Their Impact on Symptom Severity in Adolescent Patients With Anorexia Nervosa

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Perceived parental relationship characteristics, such as maternal overprotection, rejection or neglect, and peer victimisation, are suggested to be more common in patients with anorexia nervosa (AN) than in healthy controls. This study compares parental and peer relationships in adolescent patients with AN to those in a clinical ...
Armita Tschitsaz, Andrea M. Schumacher, Stefan Lerch, Andrea Wyssen, Marialuisa Cavelti, Ines Mürner‐Lavanchy, Julian Koenig, Michael Kaess, Franziska Schlensog‐Schuster   +8 more
wiley   +1 more source

A Systematic Scoping Review of Factors Contributing to Loss of Control Eating During Pregnancy

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Evidence suggests loss of control eating (LOC) during pregnancy is prevalent and linked to adverse health consequences for birthing individuals and their offspring; however, factors underlying risk for prenatal LOC remain unclear.
Riley J. Jouppi, Michele D. Levine, Rachel P. Kolko Conlon, Lydia B. Brown   +3 more
wiley   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Association of assisted reproductive technology with adverse maternal outcome: A cohort study. [PDF]

Pak J Med Sci
Liu Z, Yu L, Kang X, Zhang Y, Yan J.
europepmc   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Severe postpartum hemorrhage and the risk of adverse maternal outcome: A comparative analysis of two population-based studies in France and the Netherlands. [PDF]

Prev Med Rep
de Vries PLM, Deneux-Tharaux C, Caram-Deelder C, Goffinet F, Henriquez DDCA, Seco A, van der Bom JG, van den Akker T.   +7 more
europepmc   +1 more source

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

Exploration, EarlyView.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu, Ming‐Yu Wu, Baoping Li, Jie Li, Siyu Chen, Luojia Chen, Donghu Yu, Liupiaopiao Yang, Ziyu Hong, Huaqin Pan, Wei Xiang, Shun Feng, Jong Seung Kim, Lianrong Wang, Zhiqiang Li, Shi Chen, Meijia Gu   +16 more
wiley   +1 more source

Parents despite support networks? An intersectional analysis of disabled parenthood

Feminist Anthropology, EarlyView.
Abstract This article uses an intersectional perspective that considers patriarchal and ableist mandates to understand how family and professional support networks impact the reproductive trajectories of disabled people. The study analyzes 16 semi‐structured interviews with disabled people and 1 with a non‐disabled support worker.
Laura Sanmiquel‐Molinero, Joan Pujol‐Tarrés, Marisela Montenegro   +2 more
wiley   +1 more source

Information Shocks, Legal Liability and Physician Decisions

Health Economics, EarlyView.
ABSTRACT Physician adoption of new information about a medical procedure can affect patient outcomes. Medical malpractice law may influence physician use of such information. We analyze how physician reactions to information shocks regarding vaginal births after cesarean sections (VBACs) in the 1990s were mediated by tort reform and the standard used ...
David Mushinski, Sammy Zahran
wiley   +1 more source