Results 91 to 100 of about 224,842 (322)

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Antepartum Membrane Stripping in GBS Carriers, Is It Safe? (The STRIP-G Study). [PDF]

PLoS ONE, 2015
OBJECTIVE:Stripping of the membranes is an established and widely utilized obstetric procedure associated with higher spontaneous vaginal delivery rates, reduced need for formal induction of labor and a lower likelihood of post-term pregnancy. Due to the
Doron Kabiri, Yael Hants, Tom Raz Yarkoni, Esther Shaulof, Smadar Eventov Friedman, Ora Paltiel, Ran Nir-Paz, Wesam E Aljamal, Yossef Ezra   +8 more
doaj   +1 more source

Educational outcomes in extremely preterm children : neuropsychological correlates and predictors of attainment [PDF]

, 2011
This study assessed the impact of extremely preterm birth on academic attainment at 11 years of age, investigated neuropsychological antecedents of attainment in reading and mathematics, and examined early predictors of educational outcomes.
Achenbach T. M., Bayley N., Costeloe K., Dieter Wolke, Enid Hennessy, Grunau R. E., Johnson S., Johnson S., Kaufman A. S., Korkman M., Marlow N., Muter V., Neil Marlow, Office for National Statistics, Rickards A. L., Samantha Johnson, StataCorp, Taylor H. G., Wechsler D.   +18 more
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Maternal Diabetes Mellitus and Neonatal Outcomes in Bisha: A Retrospective Cohort Study

Medical Sciences
Background: Maternal diabetes mellitus (MDM) is associated with increased risks for adverse neonatal outcomes. However, the impact of MDM on neonatal outcomes in Bisha, a city in Saudi Arabia, is not well documented.
Abdullah Alshomrany, Elhadi Miskeen, Jaber Alfaifi, Hassan Alshamrani, Abdulmohsen Alshahrani   +4 more
doaj   +1 more source

Weekend working: a retrospective cohort study of maternal and neonatal outcomes in a large NHS delivery unit. [PDF]

, 2016
OBJECTIVES: Mandatory weekend working for NHS consultants is currently the subject of intense political debate. The Secretary of State for Health's proposed 7-day contract policy is based on the claim that such working patterns will improve patient ...
Aiken, Abigail R, Aiken, Catherine E, Brockelsby, Jeremy C, Scott, James G, Trussell, James   +4 more
core   +2 more sources

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Risks of Adverse Neonatal Outcomes in Early Adolescent Pregnancy Using Group Prenatal Care as a Strategy for Public Health Policies: A Retrospective Cohort Study in Brazil [PDF]

, 2021
Danylo José Palma Honorato, Izabela Fulone, Marcus Tolentino Silva, Luciane Cruz Lopes   +3 more
openalex   +1 more source

Costs and effects of screening and treating low risk women with a singleton pregnancy for asymptomatic bacteriuria, the ASB study [PDF]

, 2012
Background The prevalence of asymptomatic bacteriuria (ASB) in pregnancy is 2-10% and is associated with both maternal and neonatal adverse outcomes as pyelonephritis and preterm delivery.
Aleid Van Wassenaer, Alewijn Ott, AM Macejko, AR Bedford Russell, Ben Willem J Mol, BL Anderson, Brenda M Kazemier, Caroline Schneeberger, Christianne JM De Groot, Corine JM Verhoeven, DS Reeves, EH Kass, Esteriek De Miranda, F Smaill, Frans JL Reijnders, Friso MC Delemarre, J Schnarr, Jeanine A Van Der Ven, JS Dashe, JS Sheffield, K Lin, K Stenqvist, KAM Van Haaren, L Ashkenazi-Hoffnung, L Mignini, LE Nicolle, LK Millar, M Widmer, MA van Os, Martijn A Oudijk, National Collaborating Centre for Women’s and Children’s Health, Nederlandse Vereniging voor Obstetrie en Gynaecologie, Nicolette Feiertag, P Whalley, Patrick M Bossuyt, Petra N Kuiper, RIVM, SWAB, S Kenyon, Suzanne E Geerlings, TA Schlager, Tatjana E Vogelvang, TF Patterson   +41 more
core   +5 more sources

Selective Targeting of Tip Endothelial Cells as a Therapeutic Strategy for Tumor Angiogenesis

Advanced Science, EarlyView.
Doppel protein is selectively expressed in tip endothelial cells within the tumor vasculature, where it promotes tip cell motility and stabilizes the tip cell phenotype. Targeting Doppel with monoclonal antibodies disrupts this stabilization, impairs angiogenic sprouting, and reduces tumor angiogenesis, offering a selective and druggable switch for ...
Byoungmo Kim, Ha Kyeong Lee, Zulfikar Azam, Jeong Uk Choi, Riajul Wahab, Na Kyeong Lee, Yoon Gun Ko, So‐Young Choi, Se‐Ra Lee, Wan Seob Shim, Taeeung Kim, In‐San Kim, Farzana Alam, Sang Yoon Kim, Seong Who Kim, Youngro Byun, Taslim A Al‐Hilal   +16 more
wiley   +1 more source