Results 191 to 200 of about 2,016,996 (294)

Refinement of a workflow for human relevance assessment of adverse outcome pathways and associated new approach methodologies. [PDF]

Front Toxicol
van den Brand AD, Meerman JJ, Veltman CHJ, Luijten M.   +3 more
europepmc   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Multi-scale systems toxicology defines a KLF5-centered adverse outcome pathway linking DEHP exposure to pancreatic cancer progression and signaling programs relevant to therapy tolerance. [PDF]

Front Cell Dev Biol
Chen J, Pang H, Wang J, Guo J, Huang T, Zhou H.   +5 more
europepmc   +1 more source

Adversities and Development Outcomes

Recent work has shown that, conditional on survival, there are contradictory effects of adverse experiences and environments. This thesis attempts to examine whether and how various adversities may influence development outcomes and produce unequal impacts. It comprises four independent studies using evidence from China.
openaire   +2 more sources

Effectiveness and Safety of Baricitinib for Juvenile Idiopathic Arthritis–Associated Uveitis or Chronic Anterior Antinuclear Antibody–Positive Uveitis

Arthritis Care &Research, EarlyView.
Objective To evaluate the efficacy and safety of baricitinib in pediatric patients with active juvenile idiopathic arthritis–associated uveitis (JIA‐U) or chronic anterior antinuclear antibody–positive uveitis, who had an inadequate response to methotrexate (MTX) or biologic disease‐modifying antirheumatic drugs (bDMARDs).
Athimalaipet V. Ramanan, Catherine M. Guly, Gabriele Simonini, Stuart Y. Keller, Priyanka Sen, Thorsten Holzkaemper, Joana Araújo, Pierre Quartier   +7 more
wiley   +1 more source

A cut-off value for nuchal translucency in the prediction of composite adverse outcome in cystic hygroma cases. [PDF]

Rev Assoc Med Bras (1992)
Haksever M, Tanacan A, Serbetcı H, Ozkavak OO, Sahın R, Ersoy E, Kara O, Sahin D, Sahin D.   +8 more
europepmc   +1 more source

Accuracy of Diagnostic Codes and Algorithms Used to Identify Rheumatoid Arthritis and Juvenile Idiopathic Arthritis in Administrative Claims and Electronic Health Records: Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective This systematic review aimed to assess the diagnostic accuracy of algorithms used to identify rheumatoid arthritis and juvenile idiopathic arthritis in electronic health records. Methods We searched Medline, Embase, and Cochrane Central Register for Controlled Trials databases and included studies that validated case definitions against a ...
Constanza Saka‐Herrán, Jessica Bennett, Yara Alkabti, Muhammad Fatir, Barbara Clyne, Caroline McCarthy, Gráinne Tynan, Nikki Dunne, Michelle Flood, Eoghan McCarthy, Frank Moriarty   +10 more
wiley   +1 more source

Development of the EPO-Score - a multivariable tool to predict adverse outcome in infants with perinatal asphyxia undergoing therapeutic hypothermia - a retrospective study. [PDF]

Front Pediatr
van der Donk A, Schleier M, Bär A, Mulzer L, Trollmann R, Schuessler S, Hébert S, Hanslik G, Woelfle J, Reutter H, Morhart P.   +10 more
europepmc   +1 more source

Financial Distress and Its Determinants in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective To quantify the degree of financial distress and identify its determinants in adults with rheumatoid arthritis (RA) given the frequent prolonged use of expensive disease‐modifying therapies. Methods We identified adults enrolled in the FORWARD databank with either RA or noninflammatory musculoskeletal disease (NIMSKD) completing the ...
Amber Brown Keebler, Yunju Im, Sofia Pedro, Ted R. Mikuls, Edward S. Peters, Kaleb Michaud   +5 more
wiley   +1 more source

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based <i>in vitro</i> assessment with repeated exposure to whole cigarette smoke. [PDF]

Front Toxicol
Ichikawa S, Muratani S, Sano K, Erami K, Mori A, Matsumoto R, Ito S.   +6 more
europepmc   +1 more source