The FAIR AOP roadmap for 2025: Advancing findability, accessibility, interoperability, and re-usability of adverse outcome pathways. [PDF]
Mortensen HM +15 more
europepmc +1 more source
Objective Systemic lupus erythematosus (SLE) significantly impacts employment capacity. This study aimed to investigate the impact of burden of disease activity, damage, and treatment on employment outcomes and transitions in patients with SLE. Methods Using data from a single center, we analyzed employment transitions, adjusted mean disease activity ...
Javier Mencia‐Ledo +4 more
wiley +1 more source
A cut-off value for nuchal translucency in the prediction of composite adverse outcome in cystic hygroma cases. [PDF]
Haksever M +8 more
europepmc +1 more source
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell +2 more
wiley +1 more source
Adverse Outcome Pathway and Machine Learning to Predict Drug Induced Seizure Liability. [PDF]
Lane TR +4 more
europepmc +1 more source
Facial Cosmetic Therapy Use Among Patients With Systemic Sclerosis: An Australian Cohort Study
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterize patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc–related facial changes.
Zachary Warren +11 more
wiley +1 more source
Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based <i>in vitro</i> assessment with repeated exposure to whole cigarette smoke. [PDF]
Ichikawa S +6 more
europepmc +1 more source
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler +20 more
wiley +1 more source
Development of the EPO-Score - a multivariable tool to predict adverse outcome in infants with perinatal asphyxia undergoing therapeutic hypothermia - a retrospective study. [PDF]
van der Donk A +10 more
europepmc +1 more source

