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Teenage pregnancy and motherhood: How might evolutionary theory inform policy? [PDF]
, 2011 Teenage pregnancy and motherhood are considered to be pressing social concerns and, in the majority of developed countries, are often viewed as problems in need of solutions.Clegg, Helen, Sarah E. Johns, Dickins, Thomas E, Clegg, Helen T., Helen T. Clegg, Johns, Sarah E, Thomas E. Dickins, Johns, Sarah E., Dickins, Thomas E. +8 morecore +1 more sourceMetabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells
Advanced Science, EarlyView.In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai +11 morewiley +1 more sourceStudy protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes--individual patient data (IPD) meta-analysis and health economic evaluation. [PDF]
, 2014 © 2014 Ruifrok et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...Kerry, S., Mol, BW, Mol, Ben W, Owens, Julie,, Ruifrok, A., Surita, Fernanda, de Groot, Christianne J M,, Salvesen, Kjell Åsmund,, Cecatti J. G., Renault, K, Khoury, J, van Poppel M., Sagedal, Linda Reme, Petrella, Elisabetta, de Groot, C.J.M., Yeo, S, Renault K., van Poppel, Mireille N M, Coomarasamy, A, Haakstad, Lene, van Poppel, Mireille N.M., Ruifrok, AE, Haakstad, L, Riley, Richard D,, Khoury J., McAuliffe F. M., Phelan S., Renault, Kristina,, Rogozinska, E, Thangaratinam, S., Bogaerts, Annick, Vesco K., Rayanagoudar, Girish, null null, Van Poppel, M., Mol, B., Scudeller, Tânia T, Riley, Richard D., Vesco, K, Mol, Ben-Willem, Vitolo, Marcia, Bogaerts A., Stafne S. N., Arri Coomarasamy, Thangaratinam S., Haakstad L., Poston, L., Khoury, Janette, Kerry, S, Carballo, Ruben Barakat, Thangaratinam, Shakila,, Vitolo.,, Khalid Khan, Bogaerts, A., Poston, Lucilla; id_orcid, El Beltagy, Nermeen,, Astrup A., Devlieger, R, Rayanagoudar, G., Motahari, Narges, Sagedal, LR, Teede, Helena, Riley R. D., de Groot, Christianne J M, Shub, Alexis,, Cecatti, Jose G., Rauh, Kathrin,, Cecatti, Jose G,, Sally Kerry, Dodd, Jodie, Vistad, Ingvild,, Surita, Fernanda,, Khan, Khalid S., Rayanagoudar G., Luoto, Riitta, Yeo, SA, Thangaratinam, Shakila, Roberts T., Ewelina Rogozinska, Haakstad, Lene,, Coomarasamy, Arri, Lopez, Beth, Coomarasamy, Arri,, McAuliffe, FM, Vinter C., Hauner, Hans, de Groot, Christianne J, Luoto, Riitta,, Vitolo., Rayanagoudar, Girish,, Beltagy, NE, Vinter, Christina,, Kerry, Sally,, Barakat Carballo, Ruben,, van Poppel, Mireille N M,, Shakila Thangaratinam, Mol, Ben W., Dodd J., Morkved S., et al., Carballo R. B., McAuliffe, F., El Beltagy, Nermeen, Thangaratinam, Shakila; id_orcid, Facchinetti, Fabio, Shen, Gary, de Groot, C., Khan K., Lucilla Poston, i-WIP (International Weight Management in Pregnancy) Collaborative Group, Luoto, R, Rogozinska, Ewelina,, van Poppel, Mireille Nm, Stafne, SN, De Groot C. J. M., De Groot, Christianne J.M., Coomarasamy, A., Khan, K, Renault, Kristina, Mol B. W., Molyneaux, E, Roberts, Tracy, Rauh K., Girish Rayanagoudar, Khan, Khalid, McAuliffe, Fionnuala, Shub, A, Ruifrok, Anneloes E., Ruifrok, Anneloes E,, Teede, Helena,, Riley, Richard D, Lopez, B, Facchinetti F., Yeo, SeonAe, Cecatti, JG, Beltagy N. E., Vistad, Ingvild, Riley, R., Coomarasamy A., Shen, Garry X,, Owens, Julie, Khan, K., Motaharim, Narges, Sagedal, Linda Reme,, Astrup, Arne,, Hauner, Hans,, Mørkved, Siv, Rauh, K, SeonAe Yeo, Christianne JM de Groot, Yeo S., Molyneaux E., Rayanagoudar, G, Cecatti, J., Vitolo, Marcia,, Rogozinska, Ewelina, Riley, Richard D; id_orcid, Prevedel T. T. S., Poston, Lucilla,, Stafne, Signe Nilssen,, Mørkved, Siv,, Cecatti, Jose G, McAuliffe, Fionnuala M, Poston L., Phelan, S, Carballo, RB, Lund University., Ruifrok A. E., Devlieger R., McAuliffe, F.M., Riley, R.D., Phelan, Suzanne,, Yeo, Seon Ae,, Molyneaux, E., Tracy Roberts, Thangaratinam, S, Dodd, J, Roberts, Tracy,, Guelfi, K, Stafne, Signe Nilssen, Shen, Garry X, Harrison, Cheryce,, Tonstad, Serena, Carballo, R., Roberts, T., Devlieger, Roland,, Devlieger, Roland, Prevedel, Tânia T Scudeller, Guelfi, Kym,, de Groot, CJM, van Poppel, Mireille N. M., Emma Molyneaux, Kinnunen, Tarja I,, Fionnuala M McAuliffe, Bogaerts, A, Yeo, S., Mireille NM van Poppel, Vesco, Kimberly, van Poppel, Mireille N, Shen, G, Motaharim, N, Facchinetti, Fabio,, de Groot, Christianne J. M., Geiker, Nina Rica Wium,, Kinnunen, Tarja I, Vinter, Christina, Petrella, Elisabetta,, Rogozinska E., van Poppel, M.N.M., Guelfi K., Perales, Maria,, Astrup, A, Rauh, Kathrin, Mol, B.W., Facchinetti, F, Richard D Riley, Shub A., Guelfi, Kym, Prevedel, TTS, Mørkved, S, Anneloes E Ruifrok, Salvesen, Kjell Åsmund, Yeo, Seon Ae, Shen G., Motahari, Narges,, Ruifrok, Anneloes E, Barakat Carballo, Ruben, Mol, Ben-Willem,, Dodd, Jodie,, Phelan, Suzanne, Poston, Lucilla, Luoto R., Sagedal L. R., Kerry S., Geiker, Nina Rica Wium, Vinter, C, van Poppel, Mireille, Kerry, Sally, Mol, Ben Willem, Molyneaux, Emma,, Harrison, Cheryce, Khan, Khalid S.,, McAuliffe, Fionnuala M., de Groot, Christianne Jm, Khoury, Janette,, Shub, Alexis, Motaharim N., Vinter, Christina Anne; id_orcid, Astrup, Arne, Beltagy, Nermeen El, Tonstad, Serena,, van Poppel, MNM, Ben Willem Mol, Poston, L, Molyneaux, Emma, Renault, Kristina Martha, Bogaerts, Annick,, Riley, RD, Rogozinska, E., Perales, Maria, Scudeller, Tânia T,, Roberts, T, McAuliffe, Fionnuala,, Lopez B. +263 morecore +1 more sourceExposure to indoor air pollution and adverse pregnancy outcomes in low and middle-income countries: a systematic review and meta-analysis
Frontiers in Public HealthIntroductionExposure to indoor air pollution such as biomass fuel and particulate matter is a significant cause of adverse pregnancy outcomes. However, there is limited information about the association between indoor air pollution exposure and adverse ...Chala Daba, Lakew Asmare, Fekade Demeke Bayou, Mastewal Arefaynie, Anissa Mohammed, Abiyu Abadi Tareke, Awoke Keleb, Natnael Kebede, Yawkal Tsega, Abel Endawkie, Shimels Derso Kebede, Kaleab Mesfin, Eyob Tilahun Abeje, Ermias Bekele Enyew +13 moredoaj +1 more sourcePaternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit
Advanced Science, EarlyView.The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu +10 morewiley +1 more sourceNET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis
Advanced Science, EarlyView.NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang +12 morewiley +1 more sourcePharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice
Advanced Science, EarlyView.Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt +15 morewiley +1 more source